نتایج جستجو برای: wegnerâtms granulomatosis
تعداد نتایج: 5035 فیلتر نتایج به سال:
RATIONALE Orofacial granulomatosis (OFG) is a rare disease characterized by noncaseating granulomatous inflammation. The most common clinical presentation is persistent swelling of the soft tissues in the oral and maxillofacial regions. The precise cause of OFG is unknown. Corticosteroids are the first-line and best treatment, but there is lack of uniform treatment prescription and standard. It...
OBJECTIVES Recently published findings suggested that antineutrophil cytoplasmic antibodies (ANCA), particularly those with a cytoplasmic (C-ANCA) labelling pattern and targeting proteinase 3 (anti-PR3), might be markers of tuberculosis (TB). This is a critical issue, because C-ANCA/anti-PR3 were considered to be a highly specific hallmark of Wegener's granulomatosis or microscopic polyangiitis...
BACKGROUND Anti-neutrophil cytoplasmic antibodies (ANCA) is autoantibodies characteristic of vasculitis diseases. A connection between ANCA and Wegener's granulomatosis was well established. The interaction of both ANCA phenotypes (PR3-ANCA and MPO-ANCA) with leukocytes provoked cell activation, which might be involved in the pathogenesis of ANCA-related Wegener's granulomatosis. METHODS In t...
CONSIDERABLE attention has been paid in recent years to cases in which necrotic granulomata have been found in association with widespread lesions showing angiitis of the polyarteritis nodosa type. Occasionally the orbit is the site of such a granuloma. Straatsma (1957), describing the ocular manifestations of Wegener's granulomatosis, and Cutler and Blatt (1956), making a similar survey of cas...
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