What factors lead to innovative opportunities? Peter Drucker notes that some factors are changes within an organization, whereas others are changes that occur outside the organization.1 One type of change that occurs outside an organization and which history has shown to be a source of innovation is a national crisis. In this column, I examine the relationship between national crises and how on...

During much of the 21st century, natural runoff in Colorado River basin has declined, while consumption remained relatively constant, leading to historically low reservoir storage. Between January 2000 and April 2023, amount water stored Lake Mead Powell, two largest reservoirs United States, declined by 33.5 million acre feet (41.3 billion cubic meters). As total basin-wide storage was suffici...

BACKGROUND The acute crisis of metabolic decompensation in maple syrup urine disease is a potentially lethal medical emergency that requires reduction in concentrations of leucine and other branched-chain amino acids in plasma. Experience with intravenous mixtures of amino acids indicates that this can be accomplished by the synthetic forces of protein synthesis. However, these intravenous mixt...

China is facing a water resources crisis with growing concerns as to the reliable supply of water for agricultural, industrial and domestic needs. High inter-annual rainfall variability and increasing consumptive use across the country exacerbates the situation further and is a constraint on future development. For water sustainability, it is necessary to examine the differences in water demand...