BACKGROUND Small artery pathophysiology is frequently invoked as a cause of obesity-related diastolic heart failure. However, evidence to support this hypothesis is scant, particularly in humans. METHODS AND RESULTS To address this, we studied human small artery structure and function in obesity and looked for correlations between vascular parameters and diastolic function. Seventeen obese pa...

OBJECTIVES In patients undergoing corrective surgery for pectus excavatum, there is evidence of improvement in cardiopulmonary function. It is unclear how much of this improvement is attributable to improved chest wall function. Thus, we observed changes in chest wall function in response to an incremental load exercise pre- and postoperatively. METHODS Using optoelectronic plethysmography, t...

Regional myocardial function and blood flow were determined for 48 hours after permanent occlusion of the left circumflex coronary artery in conscious swine. Systolic wall thickening and end-diastolic wall thickness (EDWTh) were correlated with regional myocardial flow (RMBF) at 15 minutes, 24 and 48 hours after occlusion. Both regional function and blood flow were compared with the extent of m...

the importance of vessel structure has been shown in pathogenesis of the equine and bovine laminitis. investigation on vessel structures is necessary to diagnose the mechanism of laminitis. due to lack of literature on ovine digital arteries. ovine digital vessels were studied using corrosion casting method. the hind limbs of 15 lambs of 3 months ages were separated from tarsus joint. after the...

background: severe and prolonged physical training is associated with morphological and physiological cardiac changes, often termed as the “athlete’s heart”. echocardiographic features peculiar to elite iranian athletes have not been previously described. the aim was to examine the echocardiographic characteristics of highly trained iranian athletes involved in three different sports.   methods...

PIV measurements near a wall are generally difficult due to low seeding density, low velocity, high velocity gradient, and strong reflections. Such problems are often compounded by curved boundaries, which are commonly found in many industrial and medical applications. To systematically solve these problems, this paper presents two novel techniques for near-wall measurement, together named Inte...

To assess regional contractility in idiopathic hypertrophic subaortic stenosis (IHSS), a primary myopathic disorder with documented hyperdynamic ventricular contractions, systolic wall thickening and velocity of contraction of the septum and left ventricular posterior wall were measured in echocardiograms from 16 patients with IHSS and 16 normal subjects. The average thickening of the normal se...

Chest wall reconstruction after en-bloc tumor resection is very important to preserve functional mobility and to enhance the cosmetic effect. Because they are flexible and pliable, titanium plates are proposed to reconstruct the chest wall, even though such chest wall reconstruction has been performed in only a few cases worldwide. We present a case of a 49-year-old man with a chondrosarcoma ar...