PURPOSE The aim of this study was to review the experience of a single institution with the Deflux (Q-Med Scandinavia; Uppsala, Sweden) procedure and assess its effectiveness in reducing the incidence of urinary tract infections (UTIs) in children with vesicoureteric reflux (VUR). MATERIALS AND METHODS After institutional review board approval, the charts of 100 patients with VUR, who present...

the prevalence of vesicoureteral reflux (vur) among siblings of children with vur has been reported to be from 4.7% to 51%. the incidence of vur in the general population is less than 1% but it is high in risk groups. in a prospective study we started identifying the incidence and severity of vur and renal parenchymal lesions in the siblings of patients known to have urinary tract infection (ut...

abstract background: experience with vesicoureteral reflux (vur) differs in different centers and there are plenty of controversies. the aim of this study was to evaluate the outcome of primary vur complications and the rate of recurrence of uti. methods: the medical charts of all infants and children with primary vur who were followed up by two nephrologists were reviewed. during 19 years (198...

background: experience with vesicoureteral reflux (vur) differs in different centers and there is plenty of controversies. objective: to evaluate the outcome of primary vur complications and the rate of recurrence of uti. methods:   in a retrospective study, the medical charts of all infants and children with primary vur who were followed up by one nephrologist were reviewed.  during 16 years, ...

conclusions the results demonstrated significant associations between the il-10 (ag-1089, il-10ca) and il-12 (aa) gene polymorphisms and a highly increased risk of vur. background vesicoureteral reflux (vur) is a common childhood disorder that is characterized by the abnormal movement of urine from the bladder into the ureters or kidneys. objectives the aim of this study was to determine whethe...

Solitary crossed renal ectopia (SCRE) represents an exceedingly rare congenital disorder. Although skeletal and genitourinary abnormalities most commonly accompany this condition, vesicoureteral reflux (VUR) has been described in only a few cases. Here, we present two unique cases of SCRE complicated by high-grade VUR concomitant with posterior urethral valve in one case and hypospadias in the ...

Vesicoureteral reflux is uncommonly diagnosed and treated after puberty. The natural history of uncorrected VUR after puberty is not documented. Postpubertal patients with recurrent pyelonephritis and VUR should be considered for treatment. Ureteral reimplantation, endoscopic injections, and laparoscopic or robotic ureteral reimplantation may be utilized. Endoscopic injection is an appealing op...

In this issue of Pediatrics, Nelson and colleagues present a retrospective cross-sectional study of children ,60 months of age who underwent renal and bladder ultrasound (RBUS) and voiding cystourethrogram (VCUG). Like other studies of this topic, this is a retrospective analysis of data captured through routine care, but it is probably the largest and most well-conducted study of its kind. The...

In the mid-1980’s, the Aarhus group headed by the two pioneers in Nocturnal Enuresis research Jens-Christian Djurhuus and Jens Peter Nørgaard, reported the first data correlating the degree of Vesicoureteral Reflux (VUR) and associated nephropathy to the presence of enuresis (1). The material showed that one half of the patients with reflux also had enuresis, and that in spite of identical demo...

A 9-year-old girl with grade 4-5 right vesico-ureteric reflux (VUR) into a solitary collecting system was initially treated with endoscopic Deflux injection. Micturition cystourethrogram (MCUG) performed after 6 months showed a grade 1-2 reflux. After 3 years, MCUG repeated due to recurrent urinary tract infection (UTI), showed severe VUR. DMSA renal scan showed a non-functioning right kidney. ...