Background: The increasing prevalence of multi drug resistance (MDR) in strains Staphylococcus aureus is a major challenge the selection an appropriate therapeutic agents, especially persistent orthopaedic infections. This study investigated patterns antimicrobial and identified genetic determinants S. isolates from patients.
 Methodology: was descriptive cross-sectional hospitalized patie...

objective(s) staphylococcus aureus is a foremost source of numerous nosocomial and community acquired infections. antibiotic therapy for vancomycin resistant s. aureus (vrsa) can not promise the eradication of infections. since adhesion is the major route of infections, adhesin based vaccine could suppress s. aureus infections. fibronectin binding protein a (fnbpa) and clumping factor a (clfa) ...

Abstract Background Antimicrobial resistance is one of the most serious global health threats facing world today. The neonatal intensive care unit (NICU) a clinical environment that houses newborn infants who are highly susceptible to overwhelming infection. Early and decisive treatment with powerful anti-microbials tends be preferred choice for treating sick empirically. Prolonged exposure ant...

Staphylococcus aureus is a versatile and dangerous pathogen and one of the major causes of community-acquired and hospital-acquired infections. The rise of multidrug-resistant strains of S. aureus requires the development of new antibiotics with previously unexploited mechanisms of action, such as inhibition of the beta-ketoacyl-acyl carrier protein (ACP) synthase III (FabH). This enzyme initia...

OBJECTIVE To determine the pattern of antibiotic resistance in the clinical isolates of Staphylococcus (S.) aureus, Methicillin Resistant S. aureus (MRSA) and define the possible emergence of Vancomycin resistant S. aureus (VRSA) in Karachi. STUDY DESIGN An observational study. PLACE AND DURATION OF STUDY Essa Laboratories and Department of Molecular Genetics, Ziauddin Hospital, from Januar...

Resistance to antimicrobial agents is a major health problem that affects the whole world. Providing information on the past state of antimicrobial resistance in Libya may assist the health authorities in addressing the problem more effectively in the future. Information was obtained mainly from Highwire Press (including PubMed) search for the period 1970-2011 using the terms 'antibiotic resist...

Last winter kept us warm, covering the earth in snow daycare centers, fire stations, and universities [5e7]. and feeding a little life to dried tubers in the earth. Spring was harsh, but broke the wasteland with flowers. Summer surprised us with heavy rains. Autumn embraced us with a misty blue dawn. Another winter sees the first anniversary of our journal. This is the first anniversary issue o...