The incidence of hepatic adverse drug reactions (ADRs) remains unknown in the general population. The goal of this population-based study was to assess the incidence and seriousness of hepatic ADRs. All new cases of symptomatic drug-induced hepatic injuries were collected by 139 trained physicians (general practitioners [GPs] and specialists) between November 1997 and November 2000 in an area c...

BACKGROUND Streptokinase (SK) is an effective fibrinolytic agent for the treatment of acute myocardial infarction (AMI). The objective of the present study was to assess the adverse drug reactions (ADRs) associated with intravenous recombinant SK in patients with AMI in routine clinical practice. METHODS A national, prospective and spontaneous reporting-based pharmacovigilance program was con...

BACKGROUND Pharmacists in Japan currently play a key role in patient hospital care. Their responsibilities include filling prescriptions, checking a patient's medication history, and providing appropriate information to other health care workers. More importantly, pharmacists' interventions can also result in reductions in adverse drug reactions (ADRs) and, ultimately, in cost savings. This stu...

Discovering unknown adverse drug reactions (ADRs) in postmarketing surveillance as early as possible is highly desirable. Nevertheless, current postmarketing surveillance methods largely rely on spontaneous reports which suffer from serious underreporting, latency, and inconsistent reporting. Thus these methods are not ideal for rapidly identifying rare ADRs. The multi-agent systems paradigm is...

Objectives: To assess the Knowledge, Attitude and Practices of nursing students on monitoring reporting adverse drug reactions in a tertiary care hospital. Methodology: This questionnaire based study was conducted hospital 85 Prefinal final year students. The instrument pre designed which included Knowledge ADRs reporting, attitudes towards factors could hinder reporting. were given an educativ...

INTRODUCTION Previously, an app has been developed for healthcare professionals (HCPs) and patients to report adverse drug reactions (ADRs) to national medicines agencies and to receive drug safety information. OBJECTIVE This study aimed to assess (1) European HCPs' and patients' interest in an app for this two-way risk communication; (2) their preferences and perceptions towards specific app...

Objectives: To assess adverse drug reactions (ADRs) reporting and identify factors to improve ADR among community pharmacists in the Greater Accra Region of Ghana.Design: A quantitative cross-sectional study.Setting: Community pharmacies Ghana.Participants: We randomly selected 210 from a list Accra, Ghana. All participants had been practicing past one year, with this study being conducted June...