Salvadora persica L. is a popular chewing stick commonly known as "miswak". During our ongoing research activities on the chemical constituents of Salvadora persica roots, which is a new sulphur-containing imidazoline alkaloid 1,3-Dibenzyl-4-(1,2,3,4-tetrahydroxy-butyl)-1,3-dihydro-imidazole-2-thione, persicaline, (1) along with five known compounds (2-6) are identified. Compounds (2, 3) were r...

Background: Peanut skins are a by-product from peanut but with low socio-economic value despite having appreciable amounts of bioactive phytochemicals. Studies on-going to remove some astringent properties in and improve its values. In this study, the vitro antioxidant activity raw roasted extracts were determined hydro alcoholic medium. Materials Methods: The powders each subjected extraction ...

Schisandra chinensis is a traditional Chinese medicine that has multiple biological activities, including antioxidant, anticancer, tonic, and anti-aging effects. Deoxyschisandrin (SA) and schisandrin B (SB), the two major lignans isolated from S. chinensis, exert high antioxidant activities in vitro and in vivo by scavenging free radicals, such as reactive oxygen species (ROS). Ultraviolet B-ra...

Leaves of Premna integrifolia belong to Verbanacea is an important rasayana drug in ayurvedic medicine and are considered to be useful in the treatment of variety of ailments. The present study was aimed to assess the for its antioxidant activities. The flavonoid rich fraction, showed antioxidant activity was evaluated using the superoxide scavenging, anti lipid peroxidation, hydroxyl radical s...

A comparative study between the antioxidant properties of peel (flavedo and albedo) and juice of some commercially grown citrus fruit (Rutaceae), grapefruit (Citrus paradisi), lemon (Citrus limon), lime (Citrusxaurantiifolia) and sweet orange (Citrus sinensis) was performed. Different in vitro assays were applied to the volatile and polar fractions of peels and to crude and polar fraction of ju...

The present study was carried out to determine the free radical scavenging properties of some plants, found in Malaysia. The air-dried leaves of each plant (20 g) were soaked in distilled water (1:20; w/v) for 72 h at room temperature. Collected supernatants were tested for free radical scavenging activity against the DPPH and superoxide anion radical scavenging assays. All extracts were found ...

Chemical modification of chitosan is increasingly studied for its potential of providing new applications of chitosan. Here, a group of novel chitosan quaternary ammonium derivatives containing pyridine or amino-pyridine were designed and successfully synthesized through chemical modification of chitosan. Pyridine and amino-pyridine were used as functional groups to improve the antifungal activ...

BACKGROUND Alpinia pahangensis, a wild ginger distributed in the lowlands of Pahang, Malaysia, is used by the locals to treat flatulence. In this study, the antioxidant and cytotoxic activities of the crude aqueous methanol and fractionated extracts of Alpinia pahangensis against five different cancer and one normal cell lines were investigated. The total phenolic content of each extract and it...

The ethanol extract of B. javanica seed was fractionated with solvents of different polarities and tested for antioxidant activities by several assays including DPPH radical scavenging activity, ferric reducing antioxidant power (FRAP), ferrous ion chelating activity (FCA), and nitric oxide radical scavenging activity (NORSA) along with their polyphenolic contents. Antidiabetic activity was eva...

BACKGROUND The xanthine structure has proved to be an important scaffold in the process of developing a wide variety of biologically active molecules such as bronchodilator, hypoglycemiant, anticancer and anti-inflammatory agents. It is known that hyperglycemia generates reactive oxygen species which are involved in the progression of diabetes mellitus and its complications. Therefore, the deve...