The secosteroid hormone vitamin D has, in addition to its effects in bone metabolism also functions in the modulation of immune responses against infectious agents and in inhibiting tumorigenesis. Thus, deficiency of vitamin D is associated with several malignancies, but also with a plethora of infectious diseases. Among other communicable diseases, vitamin D deficiency is involved in the patho...

Down-regulation of microsomal androgen-dependent CYP2C1 1 is produced in male rat liver by dietary vitamin A deficiency. Decreased circulating androgen concentrations also occur in vitamin A-deficient male rats. Both effects are prevented by addition of all-trans-retinoic acid to the diet. The present study evaluated directly whether androgen deficiency may be responsible for the down-regulatio...

conclusion: this study showed positive effect of the 2000 iu/day oral vitamin d on the serum level elevation of this vitamin in reproductive women. results: at baseline the mean serum levels of vitamin d in the control group was 23.34 ± 15.87 nmol/l and in intervention group was 25.13 ± 18.46 nmol/l, that these values didn’t have any significant difference (p = 0.43), while after intervention, ...

arthralgia is a common presenting symptom of many rheumatic diseases. vitamin d deficiency may lead to progression of skeletal symptoms to definite disease in susceptible subjects. this study was conducted to determine the relationship between vitamin d deficiency and unexplained arthralgia. patients with arthralgia not related to a definite clinical condition were selected prospectively among ...

Abstract Vitamin D deficiency is associated with disease severity in asthma. We tested whether there is a causal association between vitamin D deficiency, airway smooth muscle (ASM) mass, and the development of airway hyperresponsiveness (AHR). A physiologically relevant mouse model of vitamin D deficiency was developed by raising BALB/c mice on vitamin D-deficient or -replete diets. AHR was as...

UNLABELLED After bariatric gastric bypass surgery patients are at risk of developing micronutrient deficiencies. If gastric bypass surgery is followed by a vitamin deficient diet the patients have a risk of developing vitamin-C deficiency. When spontaneous ecchymosis is observed in the skin, in at-risk patients, scurvy must be considered. When treated with large doses of vitamin-C the symptoms ...

celiac disease (also known as gluten-sensitive enteropathy or nontropical disease) is a common autoimmune disorder that caused by sensitivity to dietary gluten and related proteins in genetically sensitive individuals. the disorder may be diagnosed at any age and that affects many organ systems. celiac disease occurs in adults and children at rates approaching 0.5 to    1% of the population. we...

objective: maternal hypovitaminosis d may impair fetal growth and cause adverse pregnancy outcomes including intrauterine growth restriction and neonatal low birth weight. the aim of this study is to evaluate the relationship between maternal vitamin d status and neonate’s birth weight. materials and methods: a cross-sectional, descriptive analytical study was carried out in the nursery ward of...