OBJECTIVE Viscum album (VA) is a species of mistletoe in the family Santalaceae that is thought to have therapeutic properties for several diseases, including diabetes. In the present study, conventional experimental rat model was used with diabetes induced with streptozotocin (STZ) to evaluate effect of VA on lipid peroxidation and antioxidant system. METHODS Total of 32 adult, male Sprague-...

This study investigated the antiobesity effect of an extract of the Fomitopsis pinicola Jeseng-containing formulation (FAVA), which is a combination of four natural components: Fomitopsis pinicola Jeseng; Acanthopanax senticosus; Viscum album coloratum; and Allium tuberosum. High-fat diet- (HFD-) fed male C57BL/6J mice were treated with FAVA (200 mg/kg/day) for 12 weeks to monitor the antiobesi...

Viscum album L. has been used in the indigenous systems of medicine for treatment of headache and some inflammatory diseases. In order to evaluate this information, antinociceptive and anti-inflammatory activities of the five flavonoids (5,7-dimethoxy naringenin or 4',6'-dimethoxy chalcononaringenin) derivatives, isolated from the ethyl acetate fraction of the extract from V. album ssp. album, ...

Cyclophosphamide (CP) is an alkylating agent and its tumor cell-killing activity is mainly due to its DNA alkylation. Phosphoramide mustard and acrolein are the two active metabolites of CP. CP metabolites can react with carboxyl (-C[O]OH), mercapto (-SH), amino (-NH2), phosphate (-PO3H2) and hydroxyl (-OH) groups, and can form cross-links with DNA and proteins (Todorova et al., 2009). The prec...

Mistletoes are a group of obligate plant semi-parasites in the order Santalales. These clumps of plants growing on a wide range of host plants have been traditionally regarded as medicinal repositories. However, current scientific discoveries have validated their health potentials like never before. Their extracts containing alkaloids, viscotoxins, lectins, and polysaccharides have been evidenc...

BACKGROUND The NFkappaB signalling pathway plays an important role in chemoresistance and decreased apoptosis. One indirect way to inhibit the NFkappaB pathway is to slow down the proteasomal degradation of its inhibitor IkappaB, thus preventing NFkappaB from translocation into the nucleus. Hence, the effect of the proteasome inhibitor bortezomib (Velcade) on the cell proliferation of the MV3, ...

Aginanthus brunneus is a specie of Africa mistletoe and is hemiparasitic in nature growing on many trees. Phytochemical screening showed the presence of carbohydrates, Alkaloids, Tannins and flavonoids. The ethanolic and aqueous extracts inhibited growth of Klesiella aerogenes, Proteus spp Escherichia coli, Pseudomonas aeruginosa. Gentamycin and Cloxacillin did not exhibit any activity against ...