visceral leishmaniasis (vl) is usually treated with pentavalent antimonial drugs given alone or in combination with other drugs. the efficacy of these treatments is diminishing, however, and development of alternative treatments has been recommended.we studied 13 patients with leishmaniasis who were unresponsive to meglumine antimonate, at a dose of 20 mg/kg body weight/per day given for 30 day...

visceral leishmaniasis is a parasitic infectious disease from dogs and canids to human that is caused by protozoans of the genus leishmania. information on the prevalence of canine leishmaniasis is necessary to define control measures for zoonotic leishmaniasis. this seroepidemiological survey was performed in dogs from ahvaz district using by dat and elisa. blood was randomly collected in 38 p...

a captive adult common mynah (acridotheres tristis) died shortly after a course of seizure and opisthotonous with an illness characterized by severe lethargy, depression, loss of appetite, polyurate, and urate discoloration. abdominal distention and hepatomegly, visible over the abdominal skin, were noticed clinically. at necropsy, severe enlargement of liver with general discoloration was obvi...

background : there are several methods, such as vaccination, to control visceral leishmaniasis. although there is no efficient vaccine, it seem dna vaccination with stimulates both cellular and humoral immunity apparently is the best way. the aim of this study was cloning and expression of lack gene, a 36kd protein, as a can-didate protein for vaccination against iranian l.infantum. methods: ir...

background: immunochromatographic based rk39 antibody detection test became popular for the diagnosis of vis­ceral leishmaiasis (vl) because of high sensitivity, rapidity, easy to interpret, and cost effectiveness. however, false positive result after complete cure of the patients is the major limitation with this test. the aim of the study to access the usefulness of non-invasive samples i.e. ...