Border Disease (BD) is a condition of newborn sheep that results from congenital infection by a non-cytopathic pestivirus, occurring during the first half of gestation. The variations in expression of the virus directly relate to the age of the fetus at the time of infection. There are four distinct disease syndromes: (1) early embryonic death, (2) abortion and stillbirth, (3) birth of lambs wi...

To the Editor—By distinguishing between women who ovulated during the menstrual cycle and those who did not ovulate, Green-blat et al. [1] found that sex, contrary to generally accepted opinion , influences circulating human immunodeficiency virus (HIV) type 1 RNA levels. In ovulating women, the virus load fell during the early follicular phase through the midluteal phase. Furthermore , cervico...

BACKGROUND In two phase III vaccine trials immunisation of women previously uninfected by herpes simplex virus provided protection against genital herpes disease. In deciding policy, an evaluation of the epidemiological impact of the partial protection provided by the vaccine should be considered. METHODS A sex and sexual activity stratified deterministic differential and partial differential...

Monkeypox (MPX) is a zoonotic disease endemic in Central and West Africa and is caused by Monkeypox virus (MPXV), the most virulent Orthopoxvirus affecting humans since the eradication of Variola virus (VARV). Many aspects of the MPXV transmission cycle, including the natural host of the virus, remain unknown. African rope squirrels (Funisciurus spp.) are considered potential reservoirs of MPXV...