background: the aim of this study was to investigate the effect of hemiscorpius lepturus venom on leukocytes and the leukocyte subgroups in peripheral blood of rat. methods: in this experimental study, sixty n-mari rats were divided into three groups of 20 rats. then the rats in each group were divided into four subgroups based on the blood sampling time that was 2, 6, 24 and 48 hours after the...

b a ckground: diabetes is an important disease. this disease is a metabolic disorder characterized by hyperglycemia resulting from perturbation in insulin secretion, insulin action or both. honey bee venom contains a wide range of polypeptide agents. the principle components of bee venom are mellitin and phospholipase a2. these components increase insulin secretion from the β-cells of pancreas....

the myocardial effect of snake venoms is considered as one of the most common pathogenesis in many cases of snake envenomation. this study was under taken to investigate the effects of snake (naja naja oxiana) venom on cardiac function in experimental animals. the blood samples from all the rabbits were collected before venom injection and then 140 µg/kg venom of snake (naja naja oxiana) was in...

Stonefish are regarded as one of the most venomous fish in world. Research on stonefish venom has chiefly focused vitro and vivo neurological, cardiovascular, cytotoxic nociceptive effects venom. The last literature review was published over a decade ago, much changed field since. In this review, we have generated global map current distribution all (Synanceia) species, presented table clinical...

Vipera berus is the only viper i.e. venomous (poisonous) snake that is found in Poland. Snakebites occur rarely und usually follow attempts of catching the viper or accidental treading on it. Appropriate treatment consists of administering specific antivenom serum (antivenin). Four cases of snakebites hospitalized in 1989-1995 in the Department of Infectious Diseases of the University Medical S...

Background: To explore the oral absorption of scorpion venom an ELISA were designed in this study. Scorpions and their venom were been used for centuries as medical treatments in traditional medicine. The oral administration of drug referred as the convenient way, as there was not any publication about gastro-intestinal absorption of scorpion venom; this experiment checked oral absorption of Me...

Background: The snake, Echis carinatus, one of the most venomous snakes in Asia, possesses a deadly hemotoxic venom. It has been reported that suramin, an anti-trypansomiasis drug, can inhibit the toxic effects of some snake venoms. This study was conducted to evaluate the possible antagonistic effects of suramin against the hemorrhagic activity of the venom from an Iranian snake, Echis carinat...

background: nowadays use of specific antivenin for latrodectism is considered as the most effective treatment in the world. this study was undertaken to investigate the efficacy of specific antivenom against histopathological complications caused by latrodectus dahli venom on liver, heart and kidneys tissues within 72 h. methods: two groups were selected, each one contained 6 male new zealand r...

Potassium channels are trans-membrane proteins, which selectively transport K+ ions across cell membranes and play a key role in regulating the physiology of excitability cells and signal transduction pathways. Bothutous Schach (BS) scorpion venom consists of several polypeptides that could modulate ion channels. In this study, the effects of BS crude venom on passive and active electrophysiolo...

Background and Aims: Currently, many efforts are directed toward functional Hepatitis B virus (HBV) treatment. This is achievable by suppression of HBV surface antigen (HBsAg) secretion. In this regard, use of natural products has been the areas of interest by scientific communities. Materials and Methods: Dried Honey Bee venom was extracted for assessing its anti-HBsAg secretion potential. He...