نتایج جستجو برای: vinca minor

تعداد نتایج: 82449  

Journal: :Cancer research 1976
R J Owellen C A Hartke R M Dickerson F O Hains

A series of Vinca alkaloids were found to block polymerization of crude tubulin extracts of porcine brain in a dose-dependent manner. This appears to be a specific effect occurring at low concentrations of drug. The concentration of vinblastine that prevents polymerization by 50% was 4.3 x 10(-7) mole/liter for a tubulin concentration of 3.0 mg/ml, and this concentration is consistent with leve...

2007
Olivier Bernardi Marc Noy Dominic Welsh

A minor-closed class of graphs is a set of labelled graphs which is closed under isomorphism and under taking minors. For a minor-closed class G, we let gn be the number of graphs in G which have n vertices. A recent result of Norine et al. [12] shows that for all minor-closed class G, there is a constant c such that gn ≤ c nn!. Our main results show that the growth rate of gn is far from arbit...

Journal: :P & T : a peer-reviewed journal for formulary management 2016
Matthew Grissinger

Inadvertent intrathecal vincristine administration causes fatalities.

Journal: :The Journal of antibiotics 1990
Y Inouye K Oogose S Nakamura

When tumor cells are chronically treated with antitumor drugs such as vinca alkaloids or anthracyclines, they often acquire resistance not only to the same drugs but also to other antitumor drugs1~3). Although the mechanism of this pleiotropic drug resistance is not fully understood, decreased uptake and retention of doxorubicin ( = adriamycin, ADM) and daunorubicin ( = daunomycin, DNR) in drug...

نواری گلی (Catharanthus roseus L.)، یکی از گیاهان دارویی مهم در دنیاست که بومی ماداگاسکار می‌باشد. آلکالوئیدهای این گیاه تقسیم میتوز را مهار می‌کنند. از جنس نواری (Vinca) تنها گونه نواری علفی (Vinca herbaceae L.) در مناطق شمال ایران می‌روید. در این پژوهش آلکالوئیدهای نواری گلی و نواری علفی جدا و اثر ضدمیتوزی آنها بر سلول‌های مریستم ریشه پیاز بررسی شد. آلکالوئید‌های دو گونه نواری با حلال‌های مخت...

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