An unusual disorder of cerebellar development, rhombencephalosynapsis is a unique entity which presents with cerebellar fusion and absence of cerebellar vermis on imaging studies, often associated with supratentorial findings. No specific clinical syndrome has been described in these patients so far, and most cases are found in infancy and childhood. MRI and its multiplanar capabilities and hig...

A 76-year-old Japanese woman with essential hypertension and diabetes mellitus abruptly presented with nausea, dizziness, an occipital headache, truncal ataxia, gaze-evoked nystagmus and alternating skew deviation (ASD) with abducting eye hypertropia. Cranial computed tomography demonstrated hemorrhage in the cerebellar vermis and its vicinity. These symptoms gradually resolved within three wee...

Ad dress for Cor res pon den ce Fatih Gürbüz MD, Ankara Pediatric Hematology and Oncology Training and Research Hospital, Clinic of Pediatric Endocrinology, Ankara, Turkey E-mail: [email protected] ©Jo ur nal of Cli ni cal Re se arch in Pe di at ric En doc ri no logy, Pub lis hed by Ga le nos Pub lis hing. Dear Editor, Crouzonodermoskeletal syndrome) [Online Mendelian Inheritance in Man (OMIM)...

Histaminergic fibers are present in the molecular and granular layers of the cerebellum and have a high density in the vermis and flocullus. Evidence supports that the cerebellar histaminergic system is involved in memory consolidation. Our recent study showed that histamine injections facilitate the retention of an inhibitory avoidance task, which was abolished by pretreatment with an H2 recep...

BACKGROUND Pilomyxoid astrocytoma (PMA) has recently been accepted as an aggressive variant of pilocytic astrocytoma with distinct histopathological features. PMAs have been frequently described in the pediatric population with a predilection for the hypothalamic/chiasmatic region. CASE DESCRIPTION A 72-year-old African American male presented with 6 months of memory loss, difficulty expressi...

[3H]Choline uptake was investigated in a highly enriched preparation of glomerular particles isolated from bovine cerebellar vermis. Kinetic analysis indicates that a high-affinity choline uptake system with a relatively low maximum uptake velocity is present. At a substrate concentration of 10(-7) M, [3H]choline uptake was shown to be sodium-dependent, hemicholinium-sensitive and non-reactive ...