Tissue engineering of vascular grafts 187 1 3 Summary Background There is a considerable clinical need for a sufficient prosthetic small-diameter substitute which can compete with autologous vessels. Currently used synthetic materials have a poor performance due to high thrombogeneicity and development of intimal hyperplasia. Tissue engineering is an interesting alternative approach for vascula...

evidence acquisition a search of pubmed for studies on proximal fifth metatarsal fracture and jones fracture focusing on the classification and management was performed. the reference list of the retrieved articles was searched for additional related studies. conclusions lawrence and botte’s classification of proximal fifth metatarsal fractures is recommended by experts, due to its implication ...

Methods Replacement of ascending aorta and aortic valve from 2009 till 2013 was performed in 194 patients (18; 9,3% redo) with pathology of the aortic root. In 19 cases BioValsalva conduit was used (9,3%); in 15 pts (7,7%) allografts and in 6 (3,1%) stentless bioprosthesis were used with “full-root” technique; vascular graft conduits containing stented bioprosthesis in 16 pts (8,2%) or differen...

Coronary heart disease is the leading cause of death in the United States. An alternate therapy is needed to treat the 180,000 people each year who require coronary artery bypass surgery. Several different strategies have been explored to develop vascular graft substitutes, but so far all have proven unsatisfactory. Current engineered vessels lack sufficient strength or require many weeks to be...

A prosthetic axillo-femoral bypass graft was visualized during 111/n-labeled leukocyte scintigraphy in a patient referred for possible abdominal abscess. The presence of significant cardiac bloodpool activity raised the possibility that this uptake was due to deposition of contaminating labeled platelets rather than labeled leukocytes. An analysis of a small sample of the patient's blood confir...

Crandall CG, Davis SL. Cutaneous vascular and sudomotor responses in human skin grafts. J Appl Physiol 109: 1524–1530, 2010. First published June 17, 2010; doi:10.1152/japplphysiol.00466.2010.—Each year millions of individuals sustain burns. Within the US 40,000–70,000 individuals are hospitalized for burn-related injuries, some of which are quite severe, requiring skin grafting. The grafting p...

BACKGROUND Nanoparticles (NPs) possess several advantages as a carrier system for intracellular delivery of therapeutic agents. Rapamycin is an immunosuppressive agent which also exhibits marked antiproliferative properties. We investigated whether rapamycin-loaded NPs can reduce neointima formation of vein graft disease in a rat model. METHODS Poly(lactic-co-glycolic acid) (PLGA) NPs-contain...

The fields of vascular biology and vascular medicine are so intertwined that advances in one predict, explain, or are required for progress in the other. Bypass grafting, which once served as a “bailout” procedure,1,2 is now performed more than 600 000 times annually in the United States. In major part, this increase can be attributed to a surge in understanding of the vascular response to inju...

OBJECTIVE To assess clinical characteristics and treatment outcomes of patients with vascular injuries. MATERIALS AND METHODS We retrospectively reviewed the medical records of 378 consecutive patients with vascular injuries treated at our hospital from January 2000 to December 2012. Basic characteristics (such as gender; age; cause, site, and type of injury; and concomitant injuries) were re...

this article describes coronary artery bypass grafting by avlliath jay akrishnan et al. one of the most common reason for coronary artery bypass grafting is narrowing coronary arteries because of atherosclerosis. atherosclerosis causes chest pain (angina pectoris), myocardial infarction and sudden death. the aim of coronary artery bypass grafting is to release pain, prevention of myocardial inf...