Harken et al. had performed the first aortic valve replacement in subcoronary position in 1960 (Harken, 1960). The “caged ball” valve used in this operation pioneered to the prosthetic valves and in the last 50 years many valve types were begun to be used. The early and long term results of the patients undergone aortic valve surgery do not depend not only the patient-related factors and the ty...

By using an axisymmetric model, we numerically investigate the underlying fluid dynamics of a salp-like swimmer consisting deformable shell, front valve, and back valve. Through coordinated shell inflation/deflation valve opening/closing, uni-directional flow is created inside body in wake, which provides thrust for forward motion. Our results prove that this method capable sustained locomotion...

Introduction: Rheumatic heart disease still remains one of the leading causes of congestive heart failure and death owing to valvular pathologies, in developing countries. Valve replacement still remains the treatment of choice in such patients.The aim of this study wasto analyze the postoperative outcome of  double valve replacement (Mitral and Aortic ) in patients of rheumatic heart disease. ...

Since knowledge on hydrodynamic torque of a butterfly valve is very important for butterfly valve design, its hydrodynamic torque is investigated in this paper. In reality, the investigation of the loss coefficient and torque from some experiments will take a long time and a lot of money. This paper presents a statistical study of the flow past the butterfly valve in a static analysis using com...

Introduction: Prosthetic valve thrombosis is a rare and severe complication of valve replacement, most often encountered with a mechanical prosthesis. The significant morbidity and mortality associated with this condition warrant rapid diagnostic evaluation. Although surgery is the first-line therapy in symptomatic obstructive mechanical valve thrombosis, thrombolytic therapy has been used as a...

Background: Acceleration time (AT)/ejection (ET) ratio is a marker of aortic valve stenosis (AS) severity and predicts outcome in moderate-severe AS. Methods: We explored the association increased AT/ET on prognosis 1530 asymptomatic patients with presumably mild-moderate AS, normal ejection fraction, without known diabetes or cardiovascular disease. Patients were part SEAS study (Simvastatin E...

A computational optimization was performed for a direct-injection diesel engine using three-dimensional modeling. Fully transient CFD analyses of different valve profile strategies for the intake and compression strokes were performed to evaluate the effects on both engine performance and in-cylinder flow-field evolution. The turbulence model was used along with the second order linear upwin...

INTRODUCTION No data exist on the prevalence of primary hemostatic defects and acquired von Willebrand disease in mitral valve prolapse with severe regurgitation. METHODS Primary hemostasis was evaluated by PFA-100, von Willebrand Factor Antigen (vWF:Ag) and Ristocetin cofactor (vWF:RiCof) assays in a prospective observational trial. Sixty-five consecutive patients with mitral regurgitation (...

It remains unclear whether genetic factors contribute to the susceptibility to valve calcification. Accordingly, echocardiograms and genotyping were performed in 1871 hypertensive siblings who participated in the Hypertension Genetic Epidemiology Network Study. Genome-wide affected sibpair nonparametric linkage analysis was conducted using the allele-sharing method implemented in the Merlin com...