To identify drugs that are potentially used for the treatment of COVID-19, potency 1403 FDA-approved were evaluated using a robust pseudovirus assay and candidates further confirmed by authentic SARS-CoV-2 assay. Four compounds, Clomiphene (citrate), Vortioxetine, Vortioxetine (hydrobromide) Asenapine (hydrochloride), showed potent inhibitory effects in both virus The combination (hydrochloride...

BACKGROUND Interaction between local anesthetic solution, lidocaine hydrochloride (with and without adrenaline), and root canal irrigants such as sodium hypochlorite (NaOCl), ethylene diamine tetra-acetic acid (EDTA), and chlorhexidine (CHX) has not been studied earlier. Hence, the purpose of this in vitro study was to evaluate the chemical interaction between 2% lidocaine hydrochloride (with a...

the goal of this study was to determine the effects of ?-agonist zilpaterol hydrochloride on growth performance and carcass quality in ross broiler chicken. zilpaterol hydrochloride was daily fed at levels 0, 0.2, 0.25, 0.3 mg/kg of live body weight (lbw) from d 25 to 45 of age. eighty 308 ross female broiler chickens were employed in a 20 d feeding trial of four replicates, five birds per trea...

the aim of the present study was to develop and investigate the feasibility of delivering nebivolol as a transdermal patch by iontophoresis. the passive and electrically assisted transdermal delivery of nebivolol hydrochloride by iontophoresis will improve the therapeutic efficacy and overcome the difficulties raised in oral drug delivery. because of its extensive hepatic metabolism and low dos...

A simple and fast FI colorimetric procedure for determination of doxorubicin hydrochloride (DXH) was proposed. It is based on the redox reaction between iron (III) and DXH, resulting in an intensely red colored complex in the presence of 1, 10-orthophenantroline which can be followed by spectrophotometric measurement at λmax= 510 nm. This is an automatic way to determine doxorubicin hydrochlori...

A new rapid, specific, and convenient colorimetric method for the determination of procaine hydrochloride in pharmaceutical preparations is described. This method is based on measurement of the intensity of the orange-red color developed when procaine hydrochloride is allowed to react with 1,2-naphthoquinone-4-sulfonic acid sodium salt in aqueous solution. Beer's law is followed over 6.0--20.0 ...

In the present work, we developed a simple, sensitive and inexpensive method to determine dopamine hydrochloride using potassium ferricyanide-Fe(III) by spectrophotometry. The results show that Fe(III) is deoxidized to Fe(II) by dopamine hydrochloride at pH 4.0, and then Fe(II) reacts with potassium ferricyanide to form a soluble prussian blue (KFe(III)[Fe(II)(CN)6]). The absorbance of this pro...

Herpes simplex and basal cell carcinoma (BCC) can have similar clinical presentations due to overlapping lesional morphology. We describe the unusual case of a BCC masquerading as herpes labialis due to a possible false-positive Tzanck smear. The confounding diagnosis led to a failed trial of valacyclovir and subsequent loss of the patient for 1 year before the lesion was biopsied and diagnosed...