the majority of patients with glioblastoma multiforme (gbm) suffer dismal outcomes. adopting a broader, multi-mechanistic, multi-agent approach targeting gbm using readily available and fairly benign agents in combination with standard therapy may improve outcomes. such agents include fluoxetine, fenofibrate, cimetidine, citrulline, valacyclovir, 1,3 1-6 beta glucan, and tadalafil, among others...