To describe a nonclassical presentation and infertility management of Obstructed Hemivagina with Ipsilateral Renal Agenesis Syndrome (OHVIRA), also known as Herlyn-Werner-Wunderlich (HWWS). This is case report 31-year-old female OHVIRA syndrome who presented to community-based medical center fertility office. A her obstetric provider missed abortion (MAB) decision was made for surgical manageme...

the present study concerned with the development and characterization of metronidazole microcapsules prepared by thermal change method using different ratios (1:1, 1:2 and 1:4) of ethyl cellulose in order to select the best microcapsule formulation with a good encapsulation efficiency and drug release profile. the obtained microcapsules were discrete, spherical with free flowing properties and ...

Obstructive mullerian anomalies give rise to a spectrum of clinical presentations and are uncommon in routine gynecologic practice. The patient usually becomes symptomatic in early reproductive years. Recurrent pelvic pain, dysmenorrhea, enlarging abdominopelvic mass, and abnormal vaginal discharge are the common presenting symptoms. We describe a rare case of a mullerian anomaly getting diagno...

A thorough history and physical examination as well as laboratory testing can help narrow the differential diagnosis of amenorrhea. In patients with primary amenorrhea, the presence or absence of sexual development should direct the evaluation. Constitutional delay of growth and puberty commonly causes primary amenorrhea in patients with no sexual development. If the patient has normal pubertal...

Herlyn-Werner-Wunderlich (HWW) syndrome is a very rare congenital anomaly of the urogenital tract resulting from maldevelopment of both Mullerian and Wolffian ducts. It is characterized by the triad of uterus didelphys, obstructed hemivagina and ipsilateral renal agenesis. It generally presents at puberty shortly following menarche with the symptom of acute pelvic pain. Management of these case...

Endometriosis is characterized by the presence of endometrial tissue, localized outside the uterine cavity, such as peritoneal surface, ovaries, and rectum-vaginal septum. The prevalence is about 6 to 10%. Concerning the etiopathogenesis, the retrograde menstruation theory is accepted, although disruption in endometrial molecular biology seems to be fundamental to the development of endometrios...

The ADAMTS family comprises 19 secreted metalloproteinases that cleave extracellular matrix components and have diverse functions in numerous disease and physiological contexts. A number of them remain 'orphan' proteases and among them is ADAMTS18, which has been implicated in developmental eye disorders, platelet function and various malignancies. To assess in vivo function of ADAMTS18, we gen...

Methods This is a retrospective cohort study consisting of 669 pregnant women conducted between September, 2010 and December, 2013. The outcomes of the 297 pregnant women with primary vaginal bleeding between 14th and 22nd gestational weeks were assessed. After ruling out patients without follow-up and pregnancies ending in a spontaneous abortion, we examined 232 pregnancies compared with 327 p...

The OHVIRA syndrome classically occurs in the setting of uterine didelphys or more rarely, a septate uterus with incidence in various case series is 0.1-3.8%. Renal agenesis is the most commonly reported urologic anomaly. The typical patient with this rare condition usually presents after menarche with nonspecific symptoms of recurrent pelvic pain or dysmenorrhea but both of our patients had at...

DISCLOSURES: NONE ABSTRACT Background: The occurrence of labial fusion in an adult following episiotomy is rarely reported. Even though it is one of the simplest procedures performed in obstetric practice, an episiotomy may be complicated by labial fusion which results in difficulty in sexual intercourse and infertility. Case Report: She was a 23-year old Primipara who presented to the Gynaecol...