BACKGROUND/AIMS In Asia, the incidence of non-Hodgkin lymphoma (NHL) has increased in recent decades. Waldeyer's ring (WR) is the most common site of NHL involving the head and neck. In this study, the pathological distribution of WR-NHL and its clinical features were analyzed retrospectively. METHODS From January 2000 through December 2010, we analyzed the medical records of 328 patients fro...

PURPOSE To determine the clinical characteristics, prognosis, and treatment outcome for patients with nasal natural killer (NK)/T-cell lymphoma (N-NKTL) and Waldeyer ring NK/T-cell lymphoma (WR-NKTL). EXPERIMENTAL DESIGN A total of 145 patients with N-NKTL and 95 patients with WR-NKTL were compared. RESULTS Compared with N-NKTL, WR-NKTL exhibited distinct differences in clinical features wi...

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BACKGROUND Prefilled syringes are the standard in developed countries but logistic and financial barriers prevent their widespread use in developing countries. The current study evaluated use of a compact, prefilled, autodisable device (CPAD) to deliver pentavalent vaccine by field actors in Senegal and Vietnam. METHODS We conducted a logistic, programmatic, and anthropological study that inc...

Emerging evidence indicates that, besides dyspnea relief, an improvement in locomotor muscle oxygen delivery may also contribute to enhanced exercise tolerance following normoxic heliox (replacement of inspired nitrogen by helium) administration in patients with chronic obstructive pulmonary disease (COPD). Whether blood flow redistribution from intercostal to locomotor muscles contributes to t...

BACKGROUND Whole rye (WR) consumption seems to be associated with beneficial health effects. Although rye fiber and polyphenols are thought to be bioactive, the mechanisms behind the health effects of WR have yet to be fully identified. This study in rats was designed to investigate whether WR can influence the metabolism of n-3 and n-6 long-chain fatty acids (LCFA) and gut microbiota compositi...

Aminothiols such as WR-2721 and its active free thiol WR-1065 have previously been shown to reduce mutations resulting from ionizing radiation in exponentially growing cells. In this study, non-dividing human G0 T-lymphocytes were exposed to the aminothiol radioprotective agent, WR-1065, 30 min before or 3 h after external beam gamma-irradiation and subsequently assessed for survival and mutati...

Deep narrow-band HST imaging of the iconic spiral galaxy M101 has revealed over a thousand new Wolf Rayet (WR) candidates. We report spectrographic confirmation of 10 He iiemission line sources hosting 15 WR stars. We find WR stars present at both sub– and super– solar metalicities with WC stars favouring more metal-rich regions compared to WN stars. We investigate the association of WR stars w...