Background: Focused ultrasound surgery (FUS) is a novel noninvasive surgery that results in localized tissue necrosis without any breech of the skin or other body orifice. MRI guidance provides anatomic visualization and real time thermal feedback. Our goal is to safely extend this therapy to women who desire future pregnancies. Materials and Methods: We have undertaken 4 multisite trials of FU...

Introduction. Lipoleiomyoma (LL) is a rare, benign neoplasm, which most frequently occurs in postmenopausal women and is predominantly located in the uterus. However, extrauterine locations have been reported as well, e.g., in the broad ligament of the uterus, ovary, and peritoneum. Usually, LL is found in association with ordinary uterine leiomyomas. The incidence of this neoplasm is estimated...

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) given as a cotreatment with estrogen exhibits antiestrogenic properties on the rodent adult uterus, but less is understood regarding hormonal responsiveness of the adult uterus from animals having been exposed to TCDD during critical periods of development. We characterized the inhibitory effects of TCDD (T) exposure at gestational day 15 (GD15), 4 wee...

IntrOductIOn Induction of labour is defined as stimulation of uterine contractions before they occur spontaneously and its prevalence has increased in the United States from 9.5% of births in 1990 to 22.1% of births in 2004 [1]. Although induction of labour has recently been on the rise for purposes of convenience or to accommodate busy schedules, the main reasons include prolonged pregnancies ...

Uterine leiomyomas are the most common benign pelvic tumors in women [1, 2]. They are monoclonal tumors of the smooth muscle cells of the myometrium and consist of large amounts of extracellular matrix that contains collagen, fibronectin and proteoglycan [2, 3]. A thin pseudocapsule that is composed of areolar tissue and compressed muscle fibers usually surrounds the tumors [4]. Leiomyomas may ...

OBJECTIVE To study the effects of tamoxifen versus tamoxifen plus 13-cis-retinoic acid on the histology of uterine glands in rabbits. METHODS The experimental, randomised, controlled trial was conducted at the Army Medical College, Rawalpindi, from March 2009 to June 2009 and comprised rabbits acquired from the National Institute of Health, Islamabad. The animals were randomly divided into th...

Although premature separation of normally implanted placenta is considered the most serious complication of pregnancy, knowledge of uterine behaviour during this con­dition is meager, on the basis of electronic recording of intra-uterine pressure two type of contraction pattern has been identified.  In type I uterine tonus has values below 30mmHg  with a frequency of 4-9 contractions per 10 m...

the uterine rupture during pregnancy is a catastrophic condition resulting in both maternal and perinatal morbidity and mortality. it occurs in nearly 1% of patients with previous cesarean sections. however, uterine rupture at the site of previous iatrogenic perforation which is spontaneously healed or repaired is less reported. we present a 29-year-old woman, gravida 3 para 1, at 20 weeks of g...

OBJECTIVE While contraindications to Essure® placement have been provided by the manufacturer, there is no consensus on how best to remove these contraceptive devices. Here, we describe a non-hysterectomy removal of Essure® for a patient with a septate uterus (ESHRE Class IIb uterine malformation). CLINICAL CASE A 35yr old G4 P2 presented for removal of Essure® implants after three years of g...

Hair relaxers are used by millions of black women, possibly exposing them to various chemicals through scalp lesions and burns. In the Black Women's Health Study, the authors assessed hair relaxer use in relation to uterine leiomyomata incidence. In 1997, participants reported on hair relaxer use (age at first use, frequency, duration, number of burns, and type of formulation). From 1997 to 200...