Protein activation of urinary alpha-amylase (EC 3.2.1.1) activity was observed during an evaluation of the Du Pont aca procedure for the determination of urinary alpha-amylase. This activation effect became constant for urinary albumin concentrations exceeding 1.50 g/liter. It is recommended that urinary alpha-amylase be analyzed with sufficient albumin added to maximize this effect. The aca al...

BACKGROUND Nickel exposure can induce hyperglycaemia in rodents, but little is known about its association with abnormal glucose metabolism in humans. We aimed to investigate the association of nickel exposure with the prevalence of type 2 diabetes in Chinese adults. METHODS A total of 2115 non-institutionalized men and women aged 55 to 76 years from Beijing and Shanghai were included, and ur...

background: due to difficulty of obtaining a 24h urine (especially in children), a random urine calcium sample is recommended to detect of hypercalciuria. however, recent studies have shown that the urinary calcium/creatinine ratio varies with age and geographic areas. so, the aim of this study was determining the normal value of urinary calcium to creatinine ratio in healthy adolescent’s child...

THE question whether the proteins found in the urine in certain diseases have the same composition as the proteins in the blood is one of great importance. With the probable exception of two conditions, viz. orthostatic and Bence Jones proteinuria, it is believed that the presence of protein in the urine may be taken as a sign of impaired renal function. If the urinary protein is the same as th...

BACKGROUND Glomerular damage in IgA nephropathy (IgAN) is mediated by complement activation via the alternative and lectin pathways. Therefore, we focused on molecules stabilizing and regulating the alternative pathway C3 convertase in urine which might be associated with IgAN pathogenesis. METHODS Membrane attack complex (MAC), properdin (P), factor H (fH) and Complement receptor type 1 (CR1...

The primary constituent of urinary protein in diabetic nephropathy is albumin. Consequently, quantification of urinary albumin excretion is central to any description of diabetic renal disease. Albumin excretion can be determined from timed urine collections, and 24hour, overnight, or even shorter collection periods are used. Measurement of the urinary albumin-to-creatinine ratio in untimed uri...

Objective(s): The aim of this study was to observe the impact of sirolimus on proteinuria in streptozotocin (STZ) induced diabetic rats. Materials and Methods: Rats were given a single injection of STZ to induce diabetic rat model. Rats’ 24 hr urine was collected to test, urinary and the kidney tissues were harvested at the 8th and 20th weeks, respectively. Podocyte morphological changes were e...

conclusions vur might be more frequent in children with physiological urinary incontinence than the normal population, and might be as common as nmne with intermittent daytime incontinence. results urinary tract infection was found in 23 (34.8%) children, 17 (33.3%) and 6 (40%) patients with nmne and physiological urinary incontinence, respectively. out of 48 patients who underwent vcug, vesico...