نتایج جستجو برای: urinary albumin to creatinine ratio

تعداد نتایج: 10702664  

2016
Takashi Uzu Shin-ichi Araki Atsunori Kashiwagi Masakazu Haneda Daisuke Koya Hiroki Yokoyama Yasuo Kida Motoyoshi Ikebuchi Takaaki Nakamura Masataka Nishimura Noriko Takahara Toshiyuki Obata Nobuyuki Omichi Katsuhiko Sakamoto Ryosuke Shingu Hideki Taki Yoshio Nagai Hiroaki Tokuda Munehiro Kitada Miwa Misawa Akira Nishiyama Hiroyuki Kobori Hiroshi Maegawa

BACKGROUND In patients with diabetes, albuminuria is a risk marker of end-stage renal disease and cardiovascular events. An increased renin-angiotensin system activity has been reported to play an important role in the pathological processes in these conditions. We compared the effect of aliskiren, a direct renin inhibitor (DRI), with that of angiotensin receptor blockers (ARBs) on albuminuria ...

2017
Neerja Aggarwal Pawan Kumar Kare Parul Varshney Om Prakash Kalra Sri Venkata Madhu Basu Dev Banerjee Anil Yadav Alpana Raizada Ashok Kumar Tripathi

AIM To investigate the role of genetic variants of angiotensin converting enzyme (ACE) and angiotensinogen (AGT) genes in the antiproteinuric efficacy of ACE inhibitor therapy in diabetic nephropathy (DN) patients. METHODS In the present study, 270 type 2 diabetes mellitus patients with nephropathy were enrolled and treated with ACE inhibitor (ramipril) and followed at 6 mo for renal function...

Journal: :Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2010
Shona Methven Mark S MacGregor Jamie P Traynor Denis St J O'Reilly Christopher J Deighan

BACKGROUND Quantification of proteinuria is important in the assessment of chronic kidney disease (CKD). The aim of this study was to investigate the optimal test to identify significant proteinuria. METHODS We retrospectively assessed the relationship between total protein:creatinine ratio (TPCR), albumin:creatinine ratio (ACR) and 24-h urine total protein in 6842 patients with CKD focusing ...

2009
Stine E. Nielsen Takeshi Sugaya Lise Tarnow Maria Lajer Katrine J. Schjoedt Anne Sofie Astrup Tsuneharu Baba Hans-Henrik Parving Peter Rossing

OBJECTIVE We studied tubular and glomerular damage in type 1 diabetic patients by measuring urinary-liver fatty acid binding protein (U-LFABP) and albuminuria. Subsequently, we evaluated the effect of ACE inhibition on U-LFABP in patients with diabetic nephropathy. RESEARCH DESIGN AND METHODS We studied Caucasians with type 1 diabetes: 58 with normoalbuminuria (urinary albumin <30 mg/24 h), 4...

2017
Ian H de Boer Xiaoyu Gao Ionut Bebu Andrew N Hoofnagle John M Lachin Andrew Paterson Bruce A Perkins Amy K Saenger Michael W Steffes Bernard Zinman Mark E Molitch

Objective To evaluate biomarkers of renal tubulointerstitial damage and function in type 1 diabetes with and without diabetic kidney disease. Research design and methods Cross-sectional case-control study of Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study participants. Cases (N=43) had incident persistent estimated glomerular filtration ...

2017
Jianzhong Chen Feng Tao Bin Zhang Qingguang Chen Yan Qiu Qian Luo Yanna Gen Jiali Meng Jue Zhang Hao Lu

OBJECTIVE We aimed to explore whether squamous cell carcinoma antigen (SCC), cytokeratin 19 fragment (Cyfra21-1), neuron-specific enolase (NSE), and carcinoembryonic antigen (CEA) are elevated in diabetic nephropathy (DN) and the association between urinary albumin-to-creatinine ratio (UACR) and tumor markers in diabetic patients. METHODS Nondialysis patients with diabetes (n = 261) and 90 he...

Journal: :Journal of clinical and diagnostic research : JCDR 2013
Monika Pathania Vyas Kumar Rathaur Neeraj Yadav Aparna Jayara Aditi Chaturvedi

AIMS This study aims at assessing the predictive value of random urine A:C ratio as a screening method for Micro-albuminuria assessment in DM patients as compared to 24 hours urine albumin. SETTINGS AND DESIGN A cross sectional observational study was conducted at a tertiary care centre. One hundred ninty three patients diagnosed with DM were enrolled in the study but 14 participants didn't t...

Journal: :acta medica iranica 0
h. moayeri h. dalili

persistent microalbuminuria is predictive of nephropathy in patients with type i diabetes mellitus (dm) and has led to the development of screening programs and intervention studies. we report a longitudinal evaluation of urinary albumin excretion in 118 children with type i dm, attending a single clinic over a period of seven years. collected blood and urine samples were analyzed for glycated ...

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