Abstract Predicting how increasing intensity of human–environment interactions affects pathogen transmission is essential to anticipate changing disease risks and identify appropriate mitigation strategies. Vector-borne diseases (VBDs) are highly responsive environmental changes, but such responses notoriously difficult isolate because depends on a suite ecological social in vectors hosts that ...

INTRODUCTION The therapeutic arsenal against cutaneous leishmaniasis is very limited. Pentavalent antimonial compounds have been the drugs of choice for treatment of this disease for over 50 years. Despite their effectiveness, these drugs require daily injections, have many side effects and present prolonged healing time. OBJECTIVE To carry out a systematic literature review on the advances i...