This research relies on a combination of variable- and person-centered approaches to help improve our understanding the dimensionality workaholism construct. Our results showed that employees’ ratings simultaneously reflected global overarching construct co-existing with four specific dimensions (behavioral, motivational, emotional, cognitive workaholism) among sample 432 workers who completed ...

We have been exploring the potential of agent-based modeling methodology for socialscience research and, specifically, for illuminating theoretical complementarities of cognitive and socio-constructivist conceptualizations of learning (e.g., Abrahamson & Wilensky, 2005a). The current study advances our research by applying our methodology to pedagogy research: we investigate individual and soci...

A set of scenarios is a useful way to capture many aspects of the requirements of a system. Use Case Maps are a method for scenario capture which is good for describing multiple scenarios, including scenario interactions, for developing an architecture, and for analysing architectural alternatives. However once a component architecture is determined, Message Sequence Charts are better for devel...

Producer of macrolide antibiotic avermectin Streptomyces avermitilis UCM Ac-2179 has been isolated from Ukrainian chernozem soil, its biosynthetic activity has been increased by the traditional selection and chemical mutagenesis methods. Streptomyces avermitilis UCM Ac-2179 synthesizes avermectin with the content of anti-parasitic B-components more than 40%. Addition of exogenous Na-pyruvate (1...

Melatonin plays different physiological functions ranging from the regulation of circadian rhythms to tumor inhibition, owing to its antioxidant, immunomodulatory and anti-aging properties. Due to its pleiotropic functions, melatonin has been shown to elicit cytoprotective processes in normal cells and trigger pro-apoptotic signals in cancer cells. The therapeutic potential of melatonin analogu...

La introducción y el uso continuado de aplicaciones educativas —o con aplicación a la práctica docente— en contexto enseñanza superior universitaria están cada vez más extendidos entre profesores que confían su potencial para promover aprendizaje activo, comprometido, significativo e interactivo. Una las ha despertado grandes expectativas los últimos tiempos es Vevox. Durante curso 2021/2022, a...

In this chapter, we will study the computational complexity of manipuation for three common voting rules. We will prove that the unweighted coalitional manipulation problem (Definition 3.1.2) is NP-complete for maximin (Section 4.1) and ranked pairs (Section 4.2), and we will give a polynomial-time algorithm for UCM for Bucklin (Section 4.3). 4.1 Manipulation for Maximin is NP-complete In this ...

Umbilical cord blood (CB) is a valuable source of stem cells for transplantation, but CB transplantations are frequently complicated by delayed platelet engraftment. The reasons underlying this are unclear. We hypothesized that CBand peripheral-blood (PB)–derived megakaryocytes (MKs) respond differently to the adult hematopoietic microenvironment and to thrombopoietin (Tpo). To test this, we cu...