Due to limited X-ray contrast, the use of micro-CT in histology is so far not as widespread as predicted. While specific staining procedures-mostly using iodine-address this shortcoming, long diffusion times restrict its use in the often time-constrained daily routine. Recently, a novel staining protocol has been proposed using a biochemical preconditioning step, which increases the permeabilit...

BACKGROUND Many primary malignancies spread via lymphatic dissemination, and accurate staging therefore still relies on surgical exploration. The purpose of this study was to explore the possibility of semiautomated noninvasive nodal cancer staging using a nanoparticle-enhanced lymphotropic magnetic resonance imaging (LMRI) technique. METHODS AND FINDINGS We measured magnetic tissue parameter...

Highly mineralized natural materials such as teeth or mollusk shells boast unusual combinations of stiffness, strength and toughness currently unmatched by engineering materials. While high mineral contents provide stiffness and hardness, these materials also contain weaker interfaces with intricate architectures, which can channel propagating cracks into toughening configurations. Here we repo...

Computational 'microscopy' refers to the use of computational resources to simulate the dynamics of a molecular system. Tuned to cell membranes, this computational 'microscopy' technique is able to capture the interplay between lipids and proteins at a spatio-temporal resolution that is unmatched by other methods. Recent advances allow us to zoom out from individual atoms and molecules to supra...

We present a systematic methodology for the electromagnetic modeling of interconnected digital I/O ports. Digital drivers and receivers are represented through behavioral models based on radial basis functions expansions. Such a technique allows a very accurate representation of nonlinear/dynamic effects as well as switching behavior of real-world components by means of carefully identified dis...

Enterprise financial evaluation is an important issue. Rough set is a new technique for data mining domain application. Information Entropy, as a measurement of the average amount of information contained in an information system, is used in the classification of objectives and the analysis of information systems. In this study, establish a financial evaluation model using rough Information ent...

In this paper, the design of sliding mode control is addressed for uncertain stochastic systems modeled by Itô differential equations. There exist the parameter uncertainties in both the state and input matrices, and the unmatched external disturbance. The key feature of this work is the integration of sliding mode control method with H∞ technique such that the robustly stochastic stability wit...

mastitis is one of the most serious and costly diseases affecting dairy cattle production. in the present study, effects of a lactoferrin gene polymorphism (intron 6) on milk somatic cell count (scc) and subclinical mastitis was investigated in 121 holstein dairy cattle. two alleles of a and b and two genotypes of aa and ab were found in an ecori recognized single nucleotide polymorphism in int...

a simple inexpensive con!nuous quality control method, by means of eight basic blood coun!ng parameters, obtained from automated hematology analyzers, using pa!ent samples, is described. a few samples with low, normal and high values were selected and introduced to the instrument early in the morning as the first count, the results of which are plo#ed on the appropriate chart as dots. the same ...