Cellular processes involve large numbers of RNA molecules. The functions of these RNA molecules and their binding to molecular machines are highly dependent on their 3D structures. One of the key challenges in RNA structure prediction and modeling is predicting the spatial arrangement of the various structural elements of RNA. As RNA folding is generally hierarchical, methods involving coarse-g...

Subtle details about a polyelectrolyte's surrounding environment can dictate its structural features and potential applications. Atomic force microscopy (AFM), surface forces apparatus (SFA) measurements, and coarse-grained molecular dynamics simulations are combined to study the structure of planar polyelectrolyte brushes [poly(styrenesulfonate), PSS] in a variety of solvent conditions. More s...

Effectively localizing root causes of performance anomalies is crucial to enabling the rapid recovery and loss mitigation microservice applications in cloud. Depending on granularity that can be localized, a service operator may take different actions, e.g., restarting or migrating services if only faulty localized (namely, coarse-grained) scaling resources specific indicative metrics fine-grai...

For this paper, studies of the microstructure as well mechanical and biological properties bioinert titanium, zirconium, niobium alloys in their nanostructured (NS) ultrafine-grained (UFG) states have been completed. The NS UFG were formed by a combined two-step method severe plastic deformation (SPD), first with multidirectional forging (MDF) or pressing into symmetrical channel (PSC) at given...

Floodplain soils and reservoir sediments are known for their fine-grained structure rich organic-matter substances; therefore, they able to sorb metals other potential pollutants, which is characteristic of sink function [...]

When biomaterials are inserted in a biological environment, for instance in a body implant, proteins do quickly adsorb on the exposed surface. Such process is of fundamental importance, since it directs the subsequent cell adhesion. Here we review recent advances in this field obtained with molecular simulations. While coarse-grained models can provide important general results, as it has long ...

The work is devoted to the study of corrosion behavior TiNi alloys with original austenitic and martensitic structure in various states. In course research, it was found that rate destruction for coarse-grained ultrafine-grained Ti 49.0 Ni 51.0 different: alloy turned out be less resistant higher than state. X-ray phase analysis revealed as a result processes, change composition occurs, accompa...

The unique concept of phase reversion involving severe deformation parent austenite into martensite, followed by annealing for a short duration, whereby the strain-induced martensite reverts to austenite, was adopted obtain nano-grained/ultrafine-grained (NG/UFG) structure in Cu-bearing biomedical austenitic stainless steel resulting high strength-high ductility combination. Work hardening and ...