Are there related proteins? Lots. In mammals, Sonic is related to two other hedgehogs: Indian and Desert. When expressed appropriately, the three proteins can substitute for one another but they do have unique functions: Desert hedgehog is needed for spermatogenesis and Indian hedgehog regulates cartilage differentiation. In the zebrafish, Sonic is related to Tiggywinkle hedgehog — which is tho...

objective: pseudomonas aeruginosa is the major cause of septicemia and wound infection in burned patients. immunotraphy is the best practical way for prevention and treatment of these infections. flagella as one of the most important bacterial virulence factors has important role in attachment, motility, chemotaxis and tlr-5-dependent immune response so that it propounded as a vaccine candidate...

Richard S. Gross (Jet Propulsion laboratory, California institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91 109; ph: 1-818-354-4010; fx: 1-818-393-6890; email: Richard [email protected]. gov) Yi Chao (Jet Propulsion Laboratory, California Institute of Teclmology, 4800 Oak Grove Drive, Pasadena, CA 91 109; ph: 1-818-354-8168; fx: 1-81 8-393-6720; email: [email protected]. gov) Steven L. ...

Many believe that objective morality requires a theistic foundation. I maintain that there are sui generis objective ethical facts that do not reduce to natural or supernatural facts. On my view, objective morality does not require an external foundation of any kind. After explaining my view, I defend it against a variety of objections posed by William Wainwright, William Lane Craig, and J. P. ...

The analysis of sound and sonic devices in poetry is the focus of much poetic scholarship, and poetry scholars are becoming increasingly interested in the role that computation might play in their research. Since the nature of such sonic analysis is unique, the associated tasks are not supported by standard text analysis techniques. We introduce a formalism for analyzing sonic devices in poetry...

We show that Sonic hedgehog and patched are expressed in adjacent domains in the developing mouse retina. Treatment of cultures of perinatal mouse retinal cells with the amino-terminal fragment of Sonic hedgehog protein results in an increase in the proportion of cells that incorporate bromodeoxuridine, in total cell numbers, and in rod photoreceptors, amacrine cells and Muller glial cells, sug...

In this paper, a compensated compactness framework is established for sonic-subsonic approximate solutions to the n-dimensional(n ≥ 2) Euler equations for steady irrotational flow that may contain stagnation points. This compactness framework holds provided that the approximate solutions are uniformly bounded and satisfy H−1 loc (Ω) compactness conditions. As illustration, we show the existence...

We study the regularity of semihyperbolic patches of self-similar solutions near sonic lines to a Riemann problem for the two-dimensional (2-D) Euler system. As a result, it is verified that there exists a global solution in the semihyperbolic patch up to the sonic boundary and that the sonic boundary has C1-regularity. The study of the semihyperbolic patches of solutions for the Euler system w...

The Sonic Flashlight is an ultrasound (US) device that projects real-time US images into patients with use of a semireflective/transparent mirror. The present study evaluated the feasibility of use of the Sonic Flashlight for clinical peripherally inserted central catheter placements, originally with the mirror located inside a sterile cover (n = 15), then with the mirror outside (n = 11). Succ...

A compensated compactness framework is established for sonic-subsonic approximate solutions to the two-dimensional Euler equations for steady irrotational flows that may contain stagnation points. Only crude estimates are required for establishing compactness. It follows that the set of subsonic irrotational solutions to the Euler equations is compact; thus flows with sonic points over an obsta...