Adverse health effects have been associated with dampness and microbial exposure in buildings, but the possible pathophysiological mechanisms behind these effects are still poorly understood. Although previous studies have shown that certain microbes and microbial components have clear inflammatory and cytotoxic potentials, the complex mixture of microbial species, their spores, metabolites and...

Sporidesmin, a mycotoxin from Pithomyces chartarum is a hydrophobic molecule. It can therefore be easily incorporated in the cell membrane, where it is likely to cause changes in the bilayer organization and the properties of membrane proteins. In order to understand the redox behaviour of sporidesmin in a hydrophobic environment, we have investigated the effects of oxidized and reduced sporide...

Aim: To study the microbiological and epidemiological profile of patients with suppurative corneal ulcer presenting in a rural referral center situated Sub-Himalayan territory north India. The was conducted to evaluate epidemiology frequency mycotic keratitis among identify various fungal species as etiological agents.
 Methods: Corneal scrapings from 56 ulcers were subjected direct micros...