نتایج جستجو برای: type i insulin

تعداد نتایج: 2315061  

2011
Karolina Bäck

Insulin and insulin-like growth factor I (IGF-I) are two related peptides with similar structure. They mediate their effects by binding to their respective receptor, the insulin receptor (IR) and the IGF-I receptor (IGF-IR) and induce intracellular signalling cascades resulting in metabolic or mitogenic effects. The relative abundance of IR and IGF-IR is of importance for the type of effect tha...

Journal: :The Journal of biological chemistry 1990
A J Stewart M D Johnson F E May B R Westley

Estrogen sensitizes the MCF-7 estrogen-responsive breast cancer cell line to the mitogenic effect of insulin and the insulin-like growth factors (IGFs). This sensitization is specific for estrogen and occurs at physiological concentrations of estradiol. Dose-response experiments with insulin, IGF-I, and IGF-II suggested that the sensitization is mediated through the type I IGF receptor. Binding...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد گرمسار - دانشکده علوم انسانی 1392

the purpose of this study was to investigate the effect of task repetition on accuracy of iranian efl learners ’speaking ability. in order to achieve this purpose, a null hypothesis was developed: there is no statistically significant difference between accuracy speaking ability in iranian efl learners by use of task repetition. ; of course i should mention that, beside this null hypothesis, an...

Introduction: Resistin, as a novel adipocytokine, is associated with type 2 diabetes. The present study aimed to determine the effect of circuit resistance exercise training on plasma resistin concentration and insulin resistance in type 2 diabetic men. Methods: In this applied experimental study, 24 type 2 diabetic men were selected and randomly assigned into two exercise (n = 15, aged 46.4...

Journal: :American journal of physiology. Endocrinology and metabolism 2004
Thomas Nyström Mark K Gutniak Qimin Zhang Fan Zhang Jens Juul Holst Bo Ahrén Ake Sjöholm

GLP-1 stimulates insulin secretion, suppresses glucagon secretion, delays gastric emptying, and inhibits small bowel motility, all actions contributing to the anti-diabetogenic peptide effect. Endothelial dysfunction is strongly associated with insulin resistance and type 2 diabetes mellitus and may cause the angiopathy typifying this debilitating disease. Therefore, interventions affecting bot...

Journal: :Circulation research 2009
Ho-Jin Park Yali Zhang Chuang Du C Michael Welzig Christopher Madias Mark J Aronovitz Serban P Georgescu Isaac Naggar Bo Wang Young-Bum Kim Robert O Blaustein Richard H Karas Ronglih Liao Clayton E Mathews Jonas B Galper

RATIONALE Diabetic autonomic neuropathy (DAN), a major complication of diabetes mellitus, is characterized, in part, by impaired cardiac parasympathetic responsiveness. Parasympathetic stimulation of the heart involves activation of an acetylcholine-gated K+ current, I(KAch), via a (GIRK1)2/(GIRK4)2 K+ channel. Sterol regulatory element binding protein-1 (SREBP-1) is a lipid-sensitive transcrip...

Journal: :World Journal Of Advanced Research and Reviews 2021

The occurrence of both hyperglycaemia and hypoglycaemia, individually in combination is reported the literature, occurring various insulin resistance (IR) syndromes, to endogenous insulin, like Hirata disease, otherwise called Insulin Autoimmune syndrome (IAS), type A, I R, Type B, IR etc. exogenous administered like, antibody syndrome, (EIAS), non- classical auto immune Glycaemic disturbances ...

Journal: :فیض 0
بهرام عابدی bahram abedi department of physical education, mahallat branch, islamic azad university, mahallat, i. r. iran.بلوار آیت الله خامنه ایی، خیابان دانشگاه، دانشگاه آزاد اسلامی واحد محلات الهام اخوت elham okhovat ابراهیم بنی طالبی ebrahim banitalebi

background: regular physical exercise is a well-established therapeutic option to prevent the diabetes mellitus. the purpose of this study was to examine the effects of intense interval training (sit (and combined aerobic-strength training on serum adiponectin level and insulin resistance  in women with type 2 diabetes. materials and methods: female patients with type 2 diabetic (n=52, age: 45-...

Journal: :iranian biomedical journal 0
بهرام کاظمی bahram kazemi نگار سید negar seyed الهام مسلمی elham moslemi مژگان بنده پور mojgan bandehpour مریم بیخاف تربتی maryam bikhof torbati نوید سعادت navid saadat اکرم عیدی

background: patients with diabetes mellitus type ii suffer from hyperglycemia because they are not able to use the insulin that they produce, often due to inadequate function of insulin receptors. there are some evidences that this deficiency is inherited in a dominant autosomal manner and leads to the malfunction of the pancreatic beta cells resulting in insulin excretion disorders. in this st...

Journal: :علوم زیستی ورزشی 0
بهرام عابدی دانشیار، گروه تربیت بدنی، واحد محلات، دانشگاه آزاد اسلامی، محلات، ایران الهام اخوت کارشناس ارشد، واحد محلات، دانشگاه آزاد اسلامی، محلات، ایران

diabetes is a metabolic disorder specified by hyperglycemia following a defect in insulin secretion, insulin resistance or both. the aim of this study was to examine the effect of high-intensity interval training (hiit) on serum adiponectin levels and insulin resistance of women with type 2 diabetes. for this purpose, 35 overweight women with type 2 diabetes (age range 45-60 years, bmi 25-30 kg...

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