We show that for a large class of knots and links with complements in S admitting a hyperbolic structure, we can determine bounds on the volume of the link complement from combinatorial information given by a link diagram. Specifically, there is a universal constant C such that if a knot or link admits a prime, twist reduced diagram with at least 2 twist regions and at least C crossings per twi...

The geometrical coupling between strain and twist in double helices is investigated. Overwinding, where strain leads to further winding, is shown to be a universal property for helices, which are stretched along their longitudinal axis when the initial pitch angle is below the zero-twist angle (39.4◦). Unwinding occurs at larger pitch angles. The zero-twist angle is the unique pitch angle at th...

Epithelial-stroma interactions in the endometrium are known to be responsible for physiological functions and emergence of several pathologic lesions. Periglandular stromal cells act on endometrial cells in a paracrine manner through sex hormones. In this study, we immunohistochemically evaluated the expression of epithelial-mesenchymal transition regulators (SNAIL/SLUG, TWIST, ZEB1), adhesion ...

In breast cancer, steroid receptor coactivator-1 (SRC-1) expression positively correlates with HER2 expression and poor prognosis. In mouse mammary tumor virus-polyoma middle T (PyMT) breast cancer mouse model, SRC-1 strongly promotes mammary tumor metastasis. However, the molecular targets and mechanisms that mediate the role of SRC-1 in metastasis are unknown. In this study, SRC-1 wild-type (...

OBJECTIVE This study aimed to investigate the levels of matrix metalloproteinases (MMP)-2, MMP-9 and Twist in tumor tissue and serum from 46 cases of breast cancer patients and 31 cases of benign breast diseases patients by immunohistochemical staining and enzyme-linked immunosorbent assay, respectively. The association of gelatinase and Twist expression with clinicopathological factors was als...

BACKGROUND Despite initial indications that the transcription factor Twist could be used as a breast cancer prognostic marker, there still exists some controversy about its reliability. Thus, the aim of the present study was to assess the relationship between Twist expression and prognosis in breast carcinoma. MATERIALS AND METHODS We identified eligible studies that reported an association b...

We analyze the twist-4 contributions to Bjorken and Ellis-Jaffe sum rules for spin-dependent structure function g1(x,Q ). We investigate the anomalous dimensions of the twist-4 operators which determine the logarithmic correction to the 1/Q behavior of the twist-4 contribution by evaluating off-shell Green’s functions in both flavor non-singlet and singlet case. It is shown that the EOM operato...

Working in the light-cone gauge, we find a simple procedure to calculate the autonomous one-loop Q2 evolution of the twist-three part of the nucleon gT (x,Q2) structure function in the large-Nc limit. Our approach allows us to investigate the possibility of a similar large-Nc simplification for other higher-twist evolutions. In particular, we show that it does not occur for the twist-four part ...