نتایج جستجو برای: tumour targeting

تعداد نتایج: 205504  

Journal: :Nature materials 2011
Geoffrey von Maltzahn Ji-Ho Park Kevin Y Lin Neetu Singh Christian Schwöppe Rolf Mesters Wolfgang E Berdel Erkki Ruoslahti Michael J Sailor Sangeeta N Bhatia

Nanomedicines have enormous potential to improve the precision of cancer therapy, yet our ability to efficiently home these materials to regions of disease in vivo remains very limited. Inspired by the ability of communication to improve targeting in biological systems, such as inflammatory-cell recruitment to sites of disease, we construct systems where synthetic biological and nanotechnologic...

Journal: :ChemMedChem 2006
Jesus Razkin Véronique Josserand Didier Boturyn Zhao-hui Jin Pascal Dumy Marie Favrot Jean-Luc Coll Isabelle Texier

The direct and noninvasive in vivo visualisation of molecular processes such as ligand–receptor interaction, enzymatic activity, or gene expression, is the goal of molecular imaging. Optical imaging appears as a new complementary modality to the traditional nuclear or MRI (magnetic resonance imaging) techniques because of its low cost and fewer constraints. 4] Thus, the need for new optical pro...

Journal: :Biochemical Society transactions 2007
J Enbäck P Laakkonen

Each normal organ and pathological condition contains organ- or disease-specific molecular tags on its vasculature that constitute a vascular 'zip code' system. Tissue-selective tumour metastasis may also depend on vascular addresses. We have used phage display peptide libraries to map disease-specific differences in the vasculature. By using this technology, we have isolated several peptides w...

2015
Filipa Morais-Santos Sara Granja Vera Miranda-Gonçalves António H.J. Moreira Sandro Queirós João L. Vilaça Fernando C. Schmitt Adhemar Longatto-Filho Joana Paredes Fátima Baltazar Céline Pinheiro

BACKGROUND Most cancers, including breast cancer, have high rates of glucose consumption, associated with lactate production, a process referred as "Warburg effect". Acidification of the tumour microenvironment by lactate extrusion, performed by lactate transporters (MCTs), is associated with higher cell proliferation, migration, invasion, angiogenesis and increased cell survival. Previously, w...

Journal: :iranian journal of pharmacology and therapeutics 0
anbu jeba sunilson syam mohan mustafa ali mohamed john thomas anita gnana kumari

the aim of this study was to evaluate antitumour activity of the roots of hibiscus tiliaceus linn. against dalton’s ascitic lymphoma (dal) in swiss albino mice. a significant enhancement of mean survival time (mst) of h. tiliaceus treated tumour bearing mice was found with respect to control group. h. tiliaceus treatment was found to enhance peritoneal cell counts. when these h. tiliaceus treat...

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