نتایج جستجو برای: tumour
تعداد نتایج: 59396 فیلتر نتایج به سال:
In non-small cell lung cancer (NSCLC), stroma-resident and tumour-infiltrating macrophages may facilitate an immunosuppressive tumour microenvironment (TME) hamper immunotherapeutic responses. Analysis of tumour-associated macrophage (TAM) plasticity in NSCLC is largely lacking. We established a novel, multi-marker, dual analysis approach for assessing monocyte-derived (M?) polarisation M1/M2 p...
Impulsive control strategies have been widely used in cancer treatment and linear impulsive has always considered previous studies. We propose a novel tumour-immune model with nonlinear killing rate as state-dependent feedback control, which can better reflect the saturation effects of tumour immune cell mortalities due to chemotherapy, its dynamic behaviors are investigated. The paper aims dis...
BACKGROUND Targeted alpha therapy has been postulated to have great potential for the treatment of small clusters of tumour cells as well as small metastases. (213)Bismuth, an α-emitter with a half-life of 46 min, has shown to be effective in preclinical as well as in clinical applications. In this study, we evaluated whether (213)Bi-[DOTA(0), Tyr(3)]-octreotate ((213)Bi-DOTATATE), a (213)Bi-la...
Background and Objectives: Tumours are often low immunogenic. The role of complement, an innate immune defence system, in tumour control has begun to be elucidated, but findings conflicting. A for properdin, amplifier complement activation, recently been implicated. Materials Methods: Properdin-deficient congenic wildtype mice were injected subcutaneously with B16F10 melanoma cells. Tumour mass...
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