نتایج جستجو برای: tumor necrotizing factor alpha

تعداد نتایج: 1332861  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2002
Tobias Weber Min Lu Ladislav Andera Harald Lahm Nina Gellert Marc W Fariss Vladimir Korinek Wolfgang Sattler David S Ucker Alexei Terman Andreas Schröder Wolfgang Erl Ulf T Brunk Robert J Coffey Christian Weber Jiri Neuzil

Alpha-tocopheryl succinate (alpha-TOS), a redox-inactive analogue of vitamin E, is a strong inducer of apoptosis, whereas alpha-tocopherol (alpha-TOH) lacks apoptogenic activity (J. Neuzil et al., FASEB J., 15: 403-415, 2001). Here we investigated the possible antineoplastic activities of alpha-TOH and alpha-TOS and further explored the potential of alpha-TOS as an antitumor agent. Using nude m...

Journal: :American journal of physiology. Cell physiology 2009
Yue Wang Brent R Weil Jeremy L Herrmann Aaron M Abarbanell Jiangning Tan Troy A Markel Megan L Kelly Daniel R Meldrum

Human bone marrow mesenchymal stem cells (MSCs) are a potent source of growth factors, which are partly responsible for their beneficial paracrine effects. We reported previously that transforming growth factor-alpha (TGF-alpha), a putative mediator of wound healing and the injury response, increases the release of vascular endothelial growth factor (VEGF), augments tumor necrosis factor-alpha ...

Journal: :Journal of pediatric gastroenterology and nutrition 2005
Shaul Dollberg Ayala Lusky Brian Reichman

BACKGROUND Patent ductus arteriosus is a risk factor for the development of necrotizing enterocolitis. The use of indomethacin to treat patent ductus arteriosus in preterm infants may either decrease the incidence of necrotizing enterocolitis by stabilizing or closing the ductus arteriosus or increase its incidence by a direct constricting effect on mesenteric blood vessels. The authors sought ...

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