introduction: angiogenesis, the process of new blood vessel formation from pre-existing vessels, has important physiological roles in embryonic development, female reproduction cycle, and wound healing. it is also crucial for pathological processes in several diseases especially tumor growth and metastasis. thereby, inhibition of angiogenesis as an addition to the conventional therapies such as...

abstract meningeal melanocytoma is a rare tumor of nervous system, which originates from leptomeningeal melanocytes. the locations of melanocytoma in the nervous system are most frequently in the posterior fossa or along the spinal cord, and usually appear as an extra-axial mass. the manifestations of tumor are most often due to its compressing effect on adjacent nervous structures that causes ...

introduction: ameloblastic fibro-odontoma is a rare, benign, asymptomatic tumor. the term ameloblastic fibro-odontoma was first used by hooker in 1967 as a separate lesion from ameloblastic odontoma.   case report: this case report describes an eleven years old female with large ameloblastic fibro-odontoma in the right maxillary sinus.   conclusion: there is a low potential for recurrence after...

purpose : to report the outcome of a case of primary conjunctival rhabdomyosarcoma treated by surgical excision combined with chemotherapy case report : a 4-year-old boy presented with a visible recurrence of conjunctival mass in the left eye. the orbital magnetic resonance imaging (mri) showed the lesion was confined to the conjunctiva without orbital infiltration. histology and immunophenotyp...

context since the introduction of highly active anti-retroviral regimen for human immunodeficiency virus-1 infection, a significant increase in the incidence of hepatocellular carcinoma has been reported in patients already chronically infected with hepatitis b virus and then given this form of regimen for their retroviral infection. evidence acquisition this phenomenon was initially attributed...

background: radiotherapy plays an important role in the management of most malignant and many benign primary central nervous system (cns) tumors. radiotherapy affects both tumor cells and uninvolved normal cells; so, it is important to estimate absorbed dose to organs at risk in this kind of treatment. the aim of this study was to determine the absorbed dose to chiasma, lens, optic nerve, retin...

background: in this study, we examined the epidemiologic characteristics of childhood brain tumors in patients referred to mahak pediatric cancer treatment and research center (one of the main national referral centers for childhood malignancies in iran) for treatment. materials and methods: this cohort (simple sampling) study consisted of 198 children less than 15 year old with cns tumor refer...

background: pregnancy associated osteoporosis (pao) can lead to serious difficulties such as fragility fractures, elongated back pain and height loss in affected women. soluble receptor activator of nuclear factor-kappa b ligand (srankl) to osteoprotegerin (opg) ratio is chosen as a bone metabolism equation in many bone diseases characterized by bone resorption, such as post-menopausal osteopor...

colorectal cancer most commonly metastasizes to the liver and lung. metastatic colon carcinoma (mcc) to the breast is extremely rare. krukenberg tumor is an uncommon metastatic tumor of the ovary. case presentation: a 38 years woman presented with abdominal pain. in evaluation colon cancer was diagnosed at stage 3. folfox chemotherapy was done. after one year she developed krukenberg tumor. few...

Background: Solitary fibrous tumor (SFT) is a mesenchymal tumor which is most commonly seen in the pleura; however it can be seen in other organs such as the meninge, gastrointestinal tract, soft tissue, bone, and skin. SFT should be differentiated from other mesenchymal tumors in these organs. Immunohistochemistry plays a pivotal role for the histopathologic diagnosis...