Introduction A heart tumor in children is rare and the most primary tumor of the heart is rhabdomyoma. We report a case of cardiac mass diagnosed at 32th weeks of pregnancy while the mother had gestational diabetes Mellitus. Serial echocardiography revealed regression of the tumor; then follow up of the patient confirmed tuberous sclerosis.

Tuberous sclerosis (Pringle-Burneville disease) is a polysystemic genetic disease and occurs in the population with frequency of 1:50000. Objective study. To study neuropsychic status dynamics tuberous development children. Material Methods. Have been examined 33 children aged from 1 to 14 years, who were observed neurological pediatric department University Clinic ("Aksay") Asfendiyarov KazNMU...

Abstract Background The double inversion recovery (DIR) pulse sequence was introduced several years ago and since that it grew important value in clinical neuroimaging. We aimed to assess the added of evaluation epileptic patients. Results In mesial temporal sclerosis, measured contrast parameters (SNR, CR, CNR AI) were found be significantly higher DIR than FLAIR T2 sequences. cases focal cort...

The protein products of the tuberous sclerosis complex (TSC) genes, TSC1 and TSC2, form a complex, which inhibits the small G-protein, Ras homolog enriched in brain (Rheb). The vast majority of research regarding these proteins has focused on mammalian Target of Rapamycin (mTOR), a target of Rheb. Here, we propose that there are clinically relevant functions and targets of TSC1, TSC2 and Rheb, ...