نتایج جستجو برای: trypanocidal activity
تعداد نتایج: 1134678 فیلتر نتایج به سال:
Trypanocidal activity was found in the volatile oil of dried Dracocephalum kotschyi. GC-MS analysis determined that the major constituents of the oil were geranial (35.8%), C10H14O (26.6%), limonene (15.8%) and 1,1-dimethoxy decane (14.5%). In order to isolate the unknown biologically active monoterpene, fractionation of the volatile oil was carried out by silica gel column chromatography. The ...
The objective of this study was to investigate the seasonal variance content and chemical composition essential oil from Lantana camaraaccessions at two harvest times, analyze trypanocidal activity on Phytomonas serpens. Essential ranged 0.13 0.29% in rainy season 0.33% dryseason. compounds E-caryophyllene, α-humulene, α-curcumene germacrene D defined formation four clusters dry seasons, classi...
background: there are only four drugs for treating african trypanosomiasis, a devastating disease in sub-saharan africa. with slow discovery of better drugs, vaccination is viewed as the best method of control. we previously showed that antibodies to native trypanosoma brucei brucei tubulin inhibit the growth of trypanosomes in culture. here, we aimed to determine the effect of antibodies to ba...
Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole.
There is no effective treatment for the prevalent chronic form of Chagas' disease in Latin America. Its causative agent, the protozoan parasite Trypanosoma cruzi, has an essential requirement for ergosterol, and ergosterol biosynthesis inhibitors, such as the antifungal drug posaconazole, have potent trypanocidal activity. The antiarrhythmic compound amiodarone, frequently prescribed for the sy...
With the increase of neglected diseases such as leishmaniasis and Chagas disease, there wasa need for the search for new therapeutic alternatives that reduce the harm caused by medicineavailable for treatment. Thus, this study was performed to investigate the antiparasitic activityof the essential oil from the fruits of Piper tuberculatum Jacq, against lines of Leishmaniabraziliensis (MHOM/CO/8...
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