Objective: The objective of this study was to formulate an oral sustained release delivery system of ezetimibe mucoadhesive beads by ionic gelation technique based on sodium alginate used as a hydrophilic carrier in combination with carbopol 934P which acts as a rate modifier. Methods: Microbeads of ezetimibe were prepared using an easy method of ionotropic gelation by little modification while...

BACKGROUND Expansion and differentiation of stem cells relies on the soluble materials as well as the physical conditions of their microenvironment. Several methods have been studied in attempt to enhance the growth and differentiation rates of different adult stem cells extracted from different sources. OBJECTIVES The purpose was to improve the three-dimensional (3D) culture condition of the...

Neurotrophin-coated nanoscale magnetic beads were used to regulate the differentiation and survival of neurons. The beads coated with nerve growth factor (NGF) or brain-derived neurotrophic factor (BDNF) promoted neurite outgrowths of neurons in the same manner as soluble NGF or soluble BDNF, but beads coated with bovine serum albumin did not promote neurite outgrowths. When the volume of NGF-c...

We examine the suitability of metal-containing polystyrene beads for the calibration of a mass cytometer instrument, a single particle analyser based on an inductively coupled plasma ion source and a time of flight mass spectrometer. These metal-containing beads are also verified for their use as internal standards for this instrument. These beads were synthesized by multiple-stage dispersion p...

Abstract The period between AD 700 and 1500 has been recently labeled as “Africa’s global Golden Age.” This is particularly true for the Shay communities living on Muslim-Christian frontier in ninth to fourteenth century AD. Located center of Ethiopian highlands, faced expansion Christian kingdoms advance Muslim polities. In an increasingly violent context religious conversion war two powers, s...

The capacity of Acanthamoeba to distinguish nutritive yeast particles from non-nutritive plastic beads during phagocytosis was investigated. When cells were allowed to phagocytose yeast to capacity, endocytosis stopped and subsequent presentation of particles (either yeast or beads) did not result in further uptake. By contrast, when cells were allowed to phagocytose plastic beads to capacity a...

The aim of this paper is to provide an overview of the phases of the action research process involved in developing, implementing, and evaluating the Heart Beads program. The aim of the project is to enrich the hospital experience of children with cardiac conditions. Heart Beads involves children receiving unique beads specific to each cardiac treatment, procedure or event in recognition of the...

Aeromonas sahnonicida was isolated from salmon lice Lepeophtheirus salmonis and zooplankton in samples taken at a fish farm with an outbreak of furunculosis. Approximately 104 cells of A. salmonicida per salmon louse and 600 cells of A. salmonicida per m1 of homogenized plankton suspension were detected. By use of immunomagnetic beads coated with monoclonal antibodies against the lipopolysaccha...

The present study describes the preparation of a carrier system based on zinc-alginate beads and to evaluate its potential for the controlled release of rifampicin, the poorly water soluble drug using ionic gelation technique. The surface topology of the developed beads were analyzed by Scanning Electron Microscopy and the crosslinking process was investigated by Fourier Transform. Infrared spe...

background and objectives: probiotic yeasts are used in production of functional foods and pharmaceutical products. they play an important role in promoting and maintaining human health. until now, little work has been published on improving the survival of saccharomyces in stimulated gastrointestinal condition. material and methods: in this study the exposure of the yeast in the capsulate and ...