Multi-glycoside of Tripterygium wilfordii Hook. f.(GTW) possesses anti-inflammatory and immunosuppressive properties, and has been used as a traditional treatment for psoriasis for many years, although the underlying immunological mechanisms remain poorly understood. The T helper (Th)17 cell response is considered to play a major role in the pathogenesis of psoriasis. Th17 cells are implicated ...

Introduction: Traditionally, the diogenite meteorites have been viewed as orthopyroxenite cumulates with small amounts of olivine [1]. Several olivine-rich, harzburgite diogenites have recently been recognized and may provide insight into the occurrence of olivine on Vesta and in the HED meteorite suite [2,3]. In both the harzburgite and orthopyroxenite diogenites, olivine has been interpreted ...

BACKGROUND Triptolide, an active compound of Radix Tripterygium wilfordii, is immunosuppressive, cartilage protective and anti-inflammatory both in human and animal studies of various inflammatory and autoimmune diseases, including rheumatoid arthritis, but its therapeutic mechanism remains unclear. The aim of this study is to investigate the effects of triptolide on cartilage cytokines in the ...

A red wine from Aglianico vine was subjected to a micro-oxygenation procedure for five weeks. The wine was weekly sampled together with a non micro-oxygenated control and extracted with di-ethyl-ether in order to simplify NMR analyses. In fact, 1 H NMR spectra of the whole wine samples were dominated by water and ethanol signals which prevented visibility of the resonances generated by the less...