Little is known about the etiologic profile of triple-negative breast cancer (negative for estrogen receptor/progesterone receptor/human epidermal growth factor), a breast cancer subtype associated with high mortality and inadequate therapeutic options. We undertook this study to assess the risk for triple-negative breast cancer among women 45 years of age and younger in relation to demographic...

This paper presents a new method for the simultaneous estimation of lighting direction and shape from shading. The method estimates the shape and the lighting direction using a two step iterative process. We assume an initial (possibly incorrect) estimate of the lighting position. A stiff deformable model is then fitted to the image, assuming this lighting position. Next, a least-squares estima...

We review estimation in interval censoring models including nonparametric esti mation of a distribution function and estimation of regression models In the non parametric setting we describe computational procedures and asymptotic properties of the nonparametric maximum likelihood estimators In the regression setting we focus on the proportional hazards the proportional odds and the accelerated...

The present minireview of the place of cystatin C in clinical medicine emphasizes, and discuss the evidence, that cystatin C-based GFR-estimating equations do not require the use of vague terms like race and sex, that cystatin C-based GFR-esti mating equations are useful for both children and adults, including the elderly, that the best GFR-estimation requires simultaneous use of both cystatin ...

We present a computational case study of neuro-dynamic programming, a recent class of reinforcement learning methods. We cast the problem of play selection in American football as a stochastic shortest path Markov Decision Problem (MDP). In particular, we consider the problem faced by a quarterback in attempting to maximize the net score of an o ensive drive. The resulting optimization problem ...

We regard the simple linear calibration problem where only the response y of the regression line y = 0 + 1 t is observed with errors. The experimental conditions t are observed without error. For the errors of the observations y we assume that there may be some gross errors providing outlying observations. This situation can be modeled by a conditionally contaminated regression model. In this m...

The model of the large deflection of fabrics considering the effect of bending hysteresis was established for describing the post-buckling behavior of woven fabrics. The moment-curvature relationship of fabrics obtained by pure bending test was approximated by the Rate-model and the change in the flexural rigidity caused by the hysteresis was incorporated into the analysis. Using a nonlinear FE...

The new diimine ligand 3,8-di-n-pentyl-4,7-di(phenylethynyl)-1,10-phenanthroline (1) was used for the synthesis of a range of Pt(II) complexes, viz.[Pt(1)Cl2], [Pt(1)(C triple bond C-Ph)2], [Pt(1)(C triple bond C-Fc)2] and [Pt(1)(C triple bond C-p-C6H4-C triple bond C-Fc)2](Fc = ferrocenyl). Crystal structure analyses were performed for [Pt(1)Cl2] and [Pt(1)(C triple bond C-Ph)2] and revealed t...

Reactions of 5-[2-(trimethylsilyl)-1-ethynyl]-2,2'-bipyridine (Me3SiC-Cbpy) with Pt(bpy)C12 (bpy = 2,2'-bipyridine) and Pt(bpyC[triple bond]C-C[triple bond]Cbpy)Cl2 (bpyC[triple bond]C-C[triple bond]Cbpy=bis(2,2'-bipyridin-5-yl)butadiyne) induced isolation of Pt(bpy)(C[triple bond]Cbpy)2 (1) and Pt(bpyC[triple bond]C-C[triple bond]Cbpy)(C[triple bond]Cbpy)2 (5), respectively. Incorporating Ln(h...

allgrove syndrome also known as triple-a syndrome is an autosomal recessive disorder characterized by alacremia, achalasia and acth-resistant adrenal insufficiency. although this syndrome is rare, herein we report four cases with different clinical manifestations. they were referred to the gastrointestinal ward during a one year period with complaints of vomiting and dysphagia. the diagnosis of...