نتایج جستجو برای: tripeptides

تعداد نتایج: 564  

Journal: :Journal of medicinal chemistry 1996
J Gao X Cheng R Chen G B Sigal J E Bruce B L Schwartz S A Hofstadler G A Anderson R D Smith G M Whitesides

This paper describes the use of electrospray ionization-mass spectrometry (ESI-MS) to screen two libraries of soluble compounds to search for tight binding inhibitors for carbonic anhydrase II (EC 4.2.1.1). The two libraries, H2NO2SC6H4C(O)NH-AA1-AA2-C(O)NHCH2CH2CO2H where AA1 and AA2 are L-amino acids (library size: 289 compounds) or D-amino acids (256 compounds), were constructed by attaching...

2004
Sheena Wee Richard A.J. O’Hair W. David McFadyen

Electrospray ionization (ESI) mass spectrometry of methanolic solutions of mixtures of the copper salt (2,2′:6′,2′′-terpyridine)copper(II) nitrate monohydrate ([Cu(II)(tpy)(NO3)2]·H2O) and a tripeptide GXR (where X = 1 of the 20 naturally occurring amino acids) yielded [Cu(II)(tpy)(GXR)]•2+ ions, which were then subjected to collision induced dissociation (CID). In all but one case (GRR), these...

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