Leaf tissue of alfalfa (Medicago sativa L.) was found to contain prolinebetaine, pipecolatebetaine, hydroxyprolinebetaine, and glycinebetaine. As n-butyl esters, these chemical species exhibit molecular cations at mass/charge ratio (m/z) 200, 214, 216, and 174, respectively, when analyzed by fast atom bombardment mass spectrometry. The underivatized betaines exhibit protonated molecular ions at...

Citation: Zhang X, Li J, Xie B, Wu B, Lei S, Yao Y, He M, Ouyang H, Feng Y, Xu W and Yang S (2018) Comparative Metabolomics Analysis of Cervicitis in Human Patients and a Phenol Mucilage-Induced Rat Model Using Liquid Chromatography Tandem Mass Spectrometry. Front. Pharmacol. 9:282. doi: 10.3389/fphar.2018.00282 Comparative Metabolomics Analysis of Cervicitis in Human Patients and a Phenol Muci...

Buccoadhesive drug delivery systems have distinct advantages in comparison with oral administration. Plant exudates like gum or mucilage are being studied for their use as pharmaceutical adjuvant. The aim of this study is to evaluate the properties of the Plantago major seed mucilage as a mucoadhesive agent and propranolol hydrochloride is chosen as a model drug. Mucoadhesive tablets of propran...

S. securidaca seeds are reported to treat a variety of diseases; they contain multiple antidiabetic constituents and widely used as anti-hyperglycemic, antibacterial, well anti-hyperlipidemic agents. The present work aimed propose tablet formulations containing extracts in an attempt obtain antibacterial anti-hyperglycemic with more efficient oral hypoglycemic impact, limited side effects, high...

Loquat fruit, popular all over the world for its mild, subacid, and sweet taste, has been classified as a non-climacteric fruit with very short postharvest life. The decays quickly after harvest, losses in titratable acidity, juiciness, internal browning occurs rapidly during shelf aim of our study was to assess effects cactus pear mucilage-based coating on quality, nutraceutical value, microbi...

The effect of the time of collection on the phenolic content of the flowers of Oenothera speciosa Nutt., cultivated in Egypt, was studied. Samples collected at the early (March) and late (July) flowering periods were analyzed. Flavonoids (expressed as aglycones) and phenol acids were determined by HPLC in the hydrolyzed extracts. Samples gathered in March showed a relatively high percentage of ...

This study investigated the impact of catalase (Cat) overexpression in renal proximal tubule cells (RPTCs) on nuclear factor erythroid 2-related factor 2 (Nrf2) stimulation of angiotensinogen (Agt) gene expression and the development of hypertension and renal injury in diabetic Akita transgenic mice. Additionally, adult male mice were treated with the Nrf2 activator oltipraz with or without the...

Ocimum basilicum L. (basil) and Thymus vulgaris (thyme) are well-known medicinal plants from the Lamiaceae family. Although micromorphological characteristics mucilage production of basil thyme fruits have already been partially studied, aim this work was to examine samples collected in Serbia. The results obtained by stereomicroscope scanning electron microscopy showed that nutlets these speci...

This is a corrigendum to the article 'Inhibition of Key Digestive Enzymes Related to Diabetes and Hyperlipidemia and Protection of Liver-Kidney Functions by Trigonelline in Diabetic Rats' [Sci Pharm. 2013; 81: 233–246]. Figure 6 is replaced.