نتایج جستجو برای: triglyceride
تعداد نتایج: 20937 فیلتر نتایج به سال:
Because obesity results from an imbalance between energy input and output, with most of the excess calories stored as triglycerides (or triacylglycerols), inhibition of triglyceride synthesis may prevent or reverse obesity (1). One of the key enzymes in triglyceride synthesis is acyl coenzyme A:diacylglycerol acyltransferase (acyl CoA:diacylglycerol acyltransferase, or DGAT), which catalyzes th...
In a series of experiments with male rat livers perfused with or without 5-tetradecyloxy-2-furoic acid (TOFA) in the presence and absence of oleate, the relationships between fatty acid synthesis, oxidation, and esterification from newly synthesized and exogenous fatty acid substrates have been examined. When livers from fed rats were perfused without exogenous fatty acid substrate, 20% of the ...
Abstract Lipophagy, the selective engulfment of lipid droplets (LDs) by autophagosomes for lysosomal degradation, is critical to and energy homeostasis. Here we show that transfer protein ORP8 located on LDs mediates encapsulation autophagosomal membranes. This function independent its transporter activity achieved through direct interaction with phagophore-anchored LC3/GABARAPs. Upon lipophagy...
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