نتایج جستجو برای: triclosan

تعداد نتایج: 2220  

2016
Kim G. Harley Katherine Kogut Daniel S. Madrigal Maritza Cardenas Irene A. Vera Gonzalo Meza-Alfaro Jianwen She Qi Gavin Rana Zahedi Asa Bradman Brenda Eskenazi Kimberly L. Parra

BACKGROUND Personal care products are a source of exposure to potentially endocrine-disrupting chemicals such as phthalates, parabens, triclosan, and benzophenone-3 (BP-3) for adolescent girls. METHODS We enrolled 100 Latina girls in a youth-led, community-based participatory research intervention study to determine whether using personal care products whose labels stated they did not contain...

Journal: :Bioorganic & Medicinal Chemistry Letters 2021

Malaria is still considered as the major parasitic disease and development of artemisinin resistance does not improve this alarming situation. Based on recent identification relevant malaria targets in context, novel drug combinations were evaluated against artemisinin-sensitive artemisinin-resistant Plasmodium falciparum parasites. Corresponding hybrid molecules also synthesized for comparison...

Journal: :Environmental Science & Technology 2002

Journal: :Environmental Science & Technology 2005

2014
Andreas Obermeier Jochen Schneider Steffen Wehner Florian Dominik Matl Matthias Schieker Rüdiger von Eisenhart-Rothe Axel Stemberger Rainer Burgkart

Sutures can cause challenging surgical site infections, due to capillary effects resulting in bacteria permeating wounds. Anti-microbial sutures may avoid these complications by inhibiting bacterial pathogens. Recently, first triclosan-resistances were reported and therefore alternative substances are becoming clinically relevant. As triclosan alternative chlorhexidine, the "gold standard" in o...

2014
Sarah Forbes Curtis B. Dobson Gavin J. Humphreys Andrew J. McBain

Microbicides (biocides) play an important role in the prevention and treatment of infections. While there is currently little evidence for in-use treatment failures attributable to acquired reductions in microbicide susceptibility, the susceptibility of some bacteria can be reduced by sublethal laboratory exposure to certain agents. In this investigation, a range of environmental bacterial isol...

Journal: :Journal of visualized experiments : JoVE 2013
Lisa M Weatherly Rachel H Kennedy Juyoung Shim Julie A Gosse

Mast cells play important roles in allergic disease and immune defense against parasites. Once activated (e.g. by an allergen), they degranulate, a process that results in the exocytosis of allergic mediators. Modulation of mast cell degranulation by drugs and toxicants may have positive or adverse effects on human health. Mast cell function has been dissected in detail with the use of rat baso...

2016
Leonardo Furi Richard Haigh Zaaima J. H. Al Jabri Ian Morrissey Hong-Yu Ou Ricardo León-Sampedro Jose L. Martinez Teresa M. Coque Marco R. Oggioni

The widely used biocide triclosan selectively targets FabI, the NADH-dependent trans-2-enoyl-acyl carrier protein (ACP) reductase, which is also an important target for the development of narrow spectrum antibiotics. The analysis of triclosan resistant Staphylococcus aureus isolates had previously shown that in about half of the strains, the mechanism of triclosan resistance consists on the het...

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