نتایج جستجو برای: triclabendazole proteome

تعداد نتایج: 17375  

2014
Li Zhang Di Xiao Bo Pang Qian Zhang Haijian Zhou Lijuan Zhang Jianzhong Zhang Biao Kan

Comparative proteomics of the multiple strains within the same species can reveal the genetic variation and relationships among strains without the need to assess the genomic data. Similar to comparative genomics, core proteome and pan proteome can also be obtained within multiple strains under the same culture conditions. In this study we present the core proteome and pan proteome of four epid...

Journal: :Molecules 2009
Prahlad K Rao Qingbo Li

Understanding the biology of Mycobacterium tuberculosis is one of the primary challenges in current tuberculosis research. Investigation of mycobacterial biology using the systems biology approach has deciphered much information with regard to the bacilli and tuberculosis pathogenesis. The modulation of its environment and the ability to enter a dormant phase are the hallmarks of M. tuberculosi...

2010
Satish Kallappagoudar Parul Varma Rashmi Upadhyay Pathak Ramamoorthy Senthilkumar Rakesh K. Mishra

The nucleus is a highly structured organelle and contains many functional compartments. Although the structural basis for this complex spatial organization of compartments is unknown, a major component of this organization is likely to be the non-chromatin scaffolding called nuclear matrix (NuMat). Experimental evidence over the past decades indicates that most of the nuclear functions are at l...

2017
Jens Weingarten Melanie Weingarten Martin Wegner Walter Volknandt

The amyloid precursor protein (APP) was discovered in the 1980s as the precursor protein of the amyloid A4 peptide. The amyloid A4 peptide, also known as A-beta (Aβ), is the main constituent of senile plaques implicated in Alzheimer's disease (AD). In association with the amyloid deposits, increasing impairments in learning and memory as well as the degeneration of neurons especially in the hip...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2017
Ke Chen Ye Gao Nathan Mih Edward J O'Brien Laurence Yang Bernhard O Palsson

Maintenance of a properly folded proteome is critical for bacterial survival at notably different growth temperatures. Understanding the molecular basis of thermoadaptation has progressed in two main directions, the sequence and structural basis of protein thermostability and the mechanistic principles of protein quality control assisted by chaperones. Yet we do not fully understand how structu...

Journal: :Journal of proteome research 2014
Cheng Chang Liwei Li Chengpu Zhang Songfeng Wu Kun Guo Jin Zi Zhipeng Chen Jing Jiang Jie Ma Qing Yu Fengxu Fan Peibin Qin Mingfei Han Na Su Tao Chen Kang Wang Linhui Zhai Tao Zhang Wantao Ying Zhongwei Xu Yang Zhang Yinkun Liu Xiaohui Liu Fan Zhong Huali Shen Quanhui Wang Guixue Hou Haiyi Zhao Guilin Li Siqi Liu Wei Gu Guibin Wang Tong Wang Gong Zhang Xiaohong Qian Ning Li Qing-Yu He Liang Lin Pengyuan Yang Yunping Zhu Fuchu He Ping Xu

To estimate the potential of the state-of-the-art proteomics technologies on full coverage of the encoding gene products, the Chinese Human Chromosome Proteome Consortium (CCPC) applied a multiomics strategy to systematically analyze the transciptome, translatome, and proteome of the same cultured hepatoma cells with varied metastatic potential qualitatively and quantitatively. The results prov...

2008
Cheng S. Lee Xueping Fang Donald L. DeVoe Catherine C. Fenselau

Title of Document: TARGETING BIOMARKERS VIA CITP-BASED SELECTIVE PROTEOME ENRICHMENT Xueping Fang, Doctor of Philosophy, 2008 Directed By: Professor Cheng S. Lee Department of Chemistry and Biochemistry Besides the complexity of protein samples, probably the greatest challenge presently facing comprehensive proteome analysis is related to the large variation of protein relative abundances (>6 o...

Journal: :FEBS Letters 2021

Mitochondria contain more than 1000 different proteins, including several proteolytic enzymes. These mitochondrial proteases form a complex system that performs limited and terminal proteolysis to build the proteome, maintain, control its functions or degrade proteins peptides. During protein biogenesis, presequence cleave targeting signals obtain mature functional proteins. Processing by also ...

Journal: :Journal of Cell Biology 2001

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