BACKGROUND Soil-transmitted helminths, such as Trichuris trichiura, are of major concern in public health. Current efforts to control these helminth infections involve periodic mass treatment in endemic areas. Since these large-scale interventions are likely to intensify, monitoring the drug efficacy will become indispensible. However, studies comparing detection techniques based on sensitivity...

BACKGROUND Both tribendimidine and mebendazole are broad-spectrum drugs for anti-intestinal nematodes. We aim to assess the efficacy and safety of tribendimidine and mebendazole in patients with co-infection of Clonorchis sinensis and other helminths. METHOD We performed a randomized open-label trial in Qiyang, People's Republic of China. Eligible participants were randomly assigned to one of...

OBJECTIVE To carry out national surveys for ascertaining the current status and trends of soil-transmitted nematode infections in China, providing scientific basis for further developing control strategies. METHODS In 1988-1992 (hereinafter abbreriated as "survey in 1990"), a stratified cluster random sampling method was used in the survey. In 2001-2004 (hereinafter abbreriated as "survey in ...

Parasitic infections are generally diagnosed by professionals trained to recognize the morphological characteristics of the eggs in microscopic images of fecal smears. However, this laboratory diagnosis requires medical specialists which are lacking in many of the areas where these infections are most prevalent. In response to this public health issue, we developed a software based on pattern r...

A study on the reinfection and infection rates of soil-transmitted helminths was conducted in Kemiri Sewu, Godean District, Sleman Regency, Yogyakarta Special Province, Indonesia, from August 1988 to June 1990. A total 61 individuals rendered Ascaris lumbricoides egg-negative by drug treatment were used in the reinfection study and 412 individuals found negative for Ascaris eggs in the pretreat...

Monkeys are important experimental models for investigating human diseases. The aim of this study was to survey the alimentary tract parasites among imported vervet monkeys (Cercopithecus aethiops) to Iran. Fecal samples were collected from 40 vervets imported from Tanzania to Razi Vaccine and Serum Research Institute of Iran. Fecal samples were assessed by direct smear and Telman sedimentation...

Intestinal helminth infections are the most prevalent neglected tropical diseases, predominantly affecting rural and marginalised populations. The mainstay of diagnosis is microscopic examination faecal samples to detect parasites in form eggs, larvae cysts. In an effort improve standard care, comparative accuracy detecting hitherto used formalin-based concentration method (FC) was compared a p...

The objectives of this cross-sectional study were to identify the prevalence of soil-transmitted helminth infection in the rural population of Bali and its relation to age, gender, and geoclimatic conditions. The subjects of study were derived from four villages of different geoclimatic conditions, namely wet lowland, dry lowland, wet highland and dry highland, by a multistage, stratified rando...

A 46-year-old man presented with a history of passing bright red blood per rectum over the last one month. He also had on and off diarrhea with visible mucus in the stool for two months' duration. Further history was unremarkable, and physical examination revealed hemorrhoids which were subsequently banded. A colonoscopy was arranged in view of the prolonged diarrhea whereby an edematous and sw...