OBJECTIVE To assess the effect of high dose inhaled corticosteroids on skin. DESIGN Cross sectional study of patients receiving treatment for chest diseases. SETTING Outpatient chest clinic in a teaching hospital. PATIENTS 68 Patients divided into four groups of similar age--namely, 15 receiving long term oral prednisolone, 21 receiving high dose inhaled corticosteroids, 15 receiving low ...

background: betaine has been shown to be antioxidantand methyl donor effects in our recent studies. objectives: inthe present study, the antioxidant and methyl donor properties ofbetaine in levodopa/benserazide-mediated hyperhomocysteinemiaand levodopa-induced oxidative stress in rat's kidney wereexamined. methods: sprague-dawley male rats were dividedinto levodopa (ld), betaine (bet.), levodop...

The effect of human placenta! lactogen on the mainte nance and growth of precancerous mammary hyperplastic nodules was studied in ovariectomized, multiparous C3H/He female mice. In mice receiving injections of 0.5 mg of human placenta! lactogen twice daily for 19 days and on the morning of the 20th day, beginning the morning following bilateral ovariectomy, the number of nodules per mouse was s...

BACKGROUND Curcumin is a natural product that is often explored by patients with cancer. Weight loss due to fat and muscle depletion is a hallmark of pancreatic cancer and is associated with worse outcomes. Studies of curcumin's effects on muscularity show conflicting results in animal models. METHODS AND RESULTS Retrospective matched 1:2 case-control study to evaluate the effects of curcumin...

Objective: Neonatal  jaundice (NJ)  is  one of the  most  common  cause  of  neonatal  hospital  admission.  Phototherapy is the main therapy for hyperbilirubinemia of neonatal jaundice. The efficacy of phototherapy depends on the dose and wavelength of light used and the surface area exposed. We  increased  photons  in  mirror  covered  tunnel  phototherapy  (MCTP)  by  putting  mirrors behind...

The effect of a 6-week treatment with the calcium channel blocker nitrendipine or the angiotensin converting enzyme inhibitor enalapril on blood pressure, albuminuria, renal hemodynamics, and morphology of the nonclipped kidney was studied in rats with two-kidney, one clip renovascular hypertension. Six weeks after clipping of one renal artery, hypertensive rats (178 +/- 4 mm Hg) were randomly ...

The aim of the present study was to examine the effects of scriptaid (SCR), a histone deacetylase inhibitor (HDACi), on the in vitro and in vivo development of Wuzhishan miniature pig somatic cell nuclear transfer (SCNT) embryos. Experiment 1 compared the in vitro developmental competence of nuclear transfer embryos treated with various concentrations of SCR for 24 h. Embryos treated with 250 n...

introduction: the purpose of this study is to evaluate the effects of topical application of honey on the burn of full-thickness skin in rats. materials and methods: 40 adult female rats were divided into two groups and each group was subdivided into control and two experimental subgroups. the experiments were carried out under nitrofurazone anaesthesia. a third degree burn was carried out in t...

Background and purpose Poststroke delirium (PSD) comprises a common severe complication after stroke. However, treatment options for PSD remain insufficient. We investigated whether prophylactic melatonin supplementation may be associated with reduced risk PSD. Methods Consecutive patients admitted to the Tübingen University Stroke Unit, Tübingen, Germany, acute ischemic stroke (AIS), who under...