OBJECTIVE To evaluate the efficacy and safety of Ex-PRESS implantation (Ex-PRESS) compared to trabeculectomy in the treatment of patients with open-angle glaucoma (OAG). METHODS A comprehensive literature search using the Cochrane Methodology Register to identify randomized controlled clinical trials (RCCTs) comparing Ex-PRESS to trabeculectomy in patients with OAG. Efficacy estimates were me...

PURPOSE To evaluate the efficacy and safety of EX-PRESS implantation compared with trabeculectomy for uncontrolled open-angle glaucoma. METHODS Pertinent randomized controlled trials were identified through systematic searches of the PubMed, EMBASE, and Cochrane Library. The efficacy measures utilized were the weighted mean differences (WMDs) for the intraocular pressure reduction (IOPR), the...

Purpose: To examine the safety and efficacy of simultaneous Ahmed glaucoma valve (AGV) implantation with intravitreal and intracameral injection of bevacizumab (IVB and ICB) in patients with refractory acute neovascular glaucoma (NVG) with very high intraocular pressure (IOP) and active neovascularization of the iris (NVI) and/or the angle (NVA) Methods: In a prospective interventional study, p...

background: in previous studies, the neuroprotective effect of 17&beta-estradiol; in diffuse traumatic brain injury has been shown. this study used ici 182,780, a non-selective estrogen receptor antagonist, to test the hypothesis that the neuroprotective effect of 17&beta-estradiol; in traumatic brain injury is mediated by the estrogen receptors. methods: the ovariectomized rats were divided in...

conclusions patients presenting with spondyloptosis with no neurological deficit can be managed with in-situ fusion via pedicle screws, especially when presenting late and with minimal kyphosis. introduction traumatic thoracic spondyloptosis is caused by high energy trauma and is usually associated with severe neurological deficit. cases presenting without any neurological deficit can be diffic...

traumatic brain injury (tbi) is a significant public health concern in our country, because of placing in top three most common causes of death and substantial direct and indirect costs to society. the incidence of tbi in our country is 1.7 times of international incidence. traumatic brain injury induced by primary and secondary mechanisms that give rise to death and neurologic morbidity in pat...

conclusions toxic causes with an incidence of 49.6% were the most common cause of loss of consciousness among all age groups. results among the 123 children under investigation, 76 cases were male (61.8%) and 47 females (38.2%) with the mean age of 3.2 ± 0.64 years. the most common causes of loss of consciousness among children were as follows: toxic causes in 61 patients (49.6%), infectious ca...

In previous studies, the neuroprotective effect of progestrone in diffuse traumatic brain injury has been shown. This study used mifepristone (RU-486), a potent progesterone receptor antagonist, to evaluatethe hypothesis that the neuroprotective effect of progesterone in traumatic brain injury is mediated by the progesterone receptors. The ovariectomized rats were divided into 6 groups. Brain i...