Epstein-Barr virus (EBV) microRNAs miR-BHRF1-1, -2, and -3 have been detected in latency III-infected lymphoblasts, where they are encoded within EBNA transcripts (X. Cai, A. Schafer, S. Lu, J. P. Bilello, R. C. Desrosiers, R. Edwards, N. Raab-Traub, and B. R. Cullen, PLoS Pathog. 2:e23, 2006). In latency III-infected lymphoblasts, we have also identified a stable 1.3-kb RNA, which begins 3' to...

The complexity of a computational problem can be rigorously defined only in a model of computation including the description of the input information and the set of permissible primitive operations of which the solution algorithm must be constructed. The complexity of an algorithm is then defined as the number of primitive operations (they may be counted with weights) used in its program. If th...

For about fifteen years, the surprising success of quasi-Monte Carlo methods in finance has been raising questions that challenge our understanding of these methods. At the origin are numerical experiments performed with so-called GSobol’ and GFaure sequences by J. Traub and his team at Columbia University, following the pioneering work of S. Tezuka in 1993 on generalizations of Niederreiter (t...

Epstein-Barr virus DNA is known to have partially homologous segments, designated DL and DR, near the left and right ends of the long unique region (Raab-Traub et al., Cell 22:257-267, 1980). DL and DR are each partially composed of tandem direct repeat sequences. DL contains 11 to 14 repeats of a 124-base-pair sequence designated IR2. DR contains approximately 30 direct repeats of a 103-base-p...

Nonobese diabetic (NOD) mice are the experimental prototype of type 1 insulin-dependent diabetes mellitus (IDDM). These mice develop a characteristic autoimmune lesion in the pancreatic islets of Langerhans, where infiltrating lymphocytes destroy beta cells, resulting in hypoinsulinemia, hyperglycemia, ketoacidosis, and death. This IDDM, which closely resembles that in humans, is prevented by i...

This study examined whether evoked magnetic fields and intra- and extracellular potentials from longitudinal CA3 slices of guinea-pig can be interpreted within a single theoretical framework that incorporates ligand- and voltage-sensitive conductances in the dendrites and soma of the pyramidal cells. The 1991 CA3 mathematical model of R. D. Traub is modified to take into account the asymmetric ...

We use the informational approach of Traub and Wozniakowski [9] to study the variational form of the second order elliptic Dirichlet problem Lu = f on ü C RN. For /e Hr(Q), where r> -1, a quasi-uniform finite element method using n linear functional Jaf^i nas T7'(ß)-norm error 0(n~<r+1)/'v). We prove that it is asymptotically optimal among all methods using any information consisting of any n l...

Two families of derivative free two-point iterative methods for solving nonlinear equations are constructed. These methods use a suitable parametric function and an arbitrary real parameter. It is proved that the first family has the convergence order four requiring only three function evaluations per iteration. In this way it is demonstrated that the proposed family without memory supports the...

As a test of the usefulness of matrix methods in extending phase information of proteins, the phases of triclinic lysozyme were calculated in the range from 3"3 to 2.5 A (2000 phases) using as a starting set the phases out to 3-3 A (1500 phases) and all the amplitudes. Observed ([Fobsl) and calculated (IFmodll) amplitudes were tested separately. The agreement of the predicted phases and the ori...

Published: 22 April 2010 References 1. Aulagnier M, Verger P, Rouillon F: Efficacy of psychological debriefing in oreventing PTSD. Rev Epidemiol Sante Publique 2004, 52(1):67-79. 2. Bland SH, Valoroso L, Stranges S: long-term follow-up of psychological distress following earthquake experiences among working Italian males. J Nerv Ment Dis 2005, 193(6):420-423. 3. Taylor M, Jenkins K: The psychol...