In many developing countries, public transit plays an important role in daily life. However, few existing methods have considered the influence of public transit in their models. In this work, we present a dual-perspective view of the epidemic spreading process of the individual that involves both contamination in places (such as work places and homes) and public transit (such as buses and trai...

Introduction: Electronic portal imaging devices (EPIDs) could potentially be useful for intensity-modulated radiation therapy (IMRT) and VMAT QA. The data density, high resolution, large active area, and efficiency of the MV EPID make it an attractive option. However, EPIDs were designed as imaging devices, not dosimeters, and as a result they do not inherently measure dose in ...

While the small intestine accounts for nearly 75% of the total length of the GI tract and more than 90% of the mucosal surface area, less than 25% of all alimentary tract neoplasms and less than 2% of all malignant tumours originate from the small intestine. This could be due to the relatively rapid transit time, liquid content of stools, low bacterial population, and a high concentration of Ig...

The limited generation of neurons during adulthood is controlled by a balance between quiescence and recruitment of neural stem cells (NSCs). We use here the germinal zone of the zebrafish adult telencephalon to examine how the frequency of NSC divisions is regulated. We show, using several in vivo techniques, that progenitors transit back and forth between the quiescent and dividing state, acc...

We demonstrate that gravitational lensing can be used to discover and study planets in the habitable zones of nearby dwarf stars. If appropriate software is developed, a new generation of monitoring programs will automatically conduct a census of nearby planets in the habitable zones of dwarf stars. In addition, individual nearby dwarf stars can produce lensing events at predictable times; care...

Diffusion- and perfusion-weighted magnetic resonance imaging (DWI and PWI) was applied for stroke diagnose in 120 acute (< 48 h) ischemic stroke patients. At hyperacute (< 6 h) stage, it is difficult to find out the infarction zone in conventional T1 or T2 image, but it is easy in DWI, apparent diffusion coefficient (ADC) map; when at 3-6-hour stage it is also easy in PWI, cerebral blood flow (...

Evidence is presented to show that cells of the ependymal layer surrounding the ventricles of the mammalian (rat) forebrain act as neural stem cells (NSCs), and that these cells can be activated to divide by a combination of injury and growth factor stimulation. Several markers of asymmetric cell division (ACD), a characteristic of true stem cells, are expressed asymmetrically in the ependymal ...

Using double labeling techniques, we studied the replication of corneal epithelial stem cells that reside exclusively in the limbal zone, and their progeny transit amplifying cells. We show that corneal epithelial stem cells can be induced to enter DNA synthesis by wounding and by TPA. We demonstrate the existence of a hierarchy of TA cells; those of peripheral cornea undergo at least two round...

In contrast to cyclin D1 nulls (cD1-/-), mice without cyclin D2 (cD2-/-) lack cerebellar stellate interneurons; the reason for this is unknown. In the present study in cortex, we found a disproportionate loss of parvalbumin (PV) interneurons in cD2-/- mice. This selective reduction in PV subtypes was associated with reduced frequency of GABA-mediated inhibitory postsynaptic currents in pyramida...

Early-type stars appear to be a difficult place to look for planets astrometrically. First, they are relatively heavy, and for fixed planetary mass the astrometric signal falls inversely as the stellar mass. Second, they are relatively rare (and so tend to be more distant), and for fixed orbital separation the astrometric signal falls inversely as the distance. Nevertheless, because early-type ...